Anson Mount as David Maddox

Isla Fisher as Eveleigh Maddox

Jeff Branson as Glenn Barry

Gillian Jacobs as Sadie

Jim Parsons as Dr. Mathison

Eva Longoria as Eileen

Joanna Cassidy as Helena

John de Lancie as Victor Napoli

Michael Villar as Leo

Bryce Johnson as Ben

Annie Tedesco as Victoria Lambert

Roberto 'Sanz' Sanchez as Emilio

Christine Meier as Mrs. Peterson

Chloe Meier as Rose Peterson

Elizabeth Rowin as Betty Sayles

Christine Corpuz as Yoga Instructor

Tina D'Marco as Old Woman

Jason McNichols as Junkie

Alison Trumbull as Party Guest

Katy Yoder as Party Guest