Hugh Jackman as Logan / Wolverine

Patrick Stewart as Professor Charles Xavier

Ian McKellen as Erik Lehnsherr / Magneto

Famke Janssen as Jean Grey / Phoenix

Halle Berry as Ororo Munroe / Storm

Kelsey Grammer as Dr. Henry 'Hank' McCoy / Beast

Shawn Ashmore as Bobby Drake / Iceman

Elliot Page as Kitty Pryde

Anna Paquin as Marie / Rogue

Vinnie Jones as Cain Marko / Juggernaut

Aaron Stanford as John Allerdyce / Pyro

Ben Foster as Warren Worthington III / Angel

Michael Murphy as Warren Worthington II

Rebecca Romijn as Raven Darkholme / Mystique

James Marsden as Scott Summers / Cyclops

Dania Ramirez as Callisto

Shohreh Aghdashloo as Dr. Kavita Rao

Cameron Bright as Jimmy / Leech

Josef Sommer as The President

Bill Duke as Trask

Daniel Cudmore as Peter Rasputin / Colossus

Eric Dane as James Madrox / Multiple Man

Desiree Zurowski as Mrs. Grey

Adrian Hough as Mr. Grey

Haley Ramm as Young Jean Grey

Chris Claremont as Lawnmower Man

Stan Lee as Waterhose Man

Cayden Boyd as Young Angel

Tanya Newbould as Dr. McCoy's Assistant

Anthony Heald as FBI Mystique Interrogator

Connor Widdows as Jones

Kea Wong as Jubilation Lee / Jubilee

Shauna Kain as Theresa Rourke Cassidy / Siryn

Luke Pohl as Flea

Julian Richings as Mutant Theatre Organizer

Lloyd Adams as Lizard Man

Richard Yee as Little Phat

Via Saleaumua as Phat

Meiling Melançon as Elizabeth Braddock / Psylocke

Omahyra Mota as Phillipa Sontag / Arclight

Clayton Watmough as Glob Herman

Ken Leung as Kid Omega

Julian Christopher as Prison Truck Guard #1

Brad Kelly as Prison Truck Guard #2

Makenzie Vega as Prison Truck Little Girl

Mi-Jung Lee as Newscaster

Benita Ha as Worthington Technician

Ron James as Prison Truck Driver

R. Lee Ermey as Sergeant (voice)

Lance Gibson as Spike

Aaron Pearl as Team Leader

Chelah Horsdal as Minivan Mother

John Pyper-Ferguson as Minivan Father

Brenna O'Brien as Minivan Daughter

Justin Callan as Minivan Son #1

Alex Ferris as Minivan Son #2

Peter Kawasaki as Photographer

Ron Blecker as Commander

Emy Aneke as Alcatraz Lieutenant

David Smith as Omega Mutie

Olivia Williams as Dr. Moira MacTaggert

Tony Stef'Ano as Mutant (uncredited)