Melissa Gilbert as Laura Ingalls Wilder

Dean Butler as Almanzo Wilder

Richard Bull as Nels Oleson

Victor French as Isaiah Edwards

Kevin Hagen as Dr. Hiram Baker

Allison Balson as Nancy Oleson

Stan Ivar as John Carter

Pamela Roylance as Sarah Carter

Lindsay Kennedy as Jeb Carter

David Friedman as Jason Carter

Shannen Doherty as Jenny Wilder

Leslie Landon as Etta Plum

Robert Casper as Sherwood Montague

Patricia Pearcy as Elsa Norris

Robin Clarke as Patrick Norris

Harvey Vernon as Mr. Baker

Joel Graves as Sam

J.S. 'Joe' Young as Beggar

Colin Hamilton as Mr. Dodsworthy

Stephen Roberts as Dr. Langley

Kate Williamson as Nurse

Robert L. Lee as Ticket Agent

Henry Kendrick as Sheriff #1 (as Hank Kendrick)

Dick Armstrong as Sheriff #2 (as Richard Armstrong)

Jack Dunlap as Sheriff #3

Garin Bougie as Butcher Boy

Ruth Foster as Melinda Foster

Jack Lilley as Stagecoach Driver

Ike Eisenmann as Erich Schiller (uncredited)

Angella Kaye as School Girl (uncredited)

Michael Landon as Charles Ingalls (voice) (uncredited)

Jennifer Steffin as Rose Wilder (uncredited)

Michelle Steffin as Rose Wilder (uncredited)