Benedict Cumberbatch as Dr. Stephen Strange

Chiwetel Ejiofor as Mordo

Rachel McAdams as Dr. Christine Palmer

Benedict Wong as Wong

Mads Mikkelsen as Kaecilius

Tilda Swinton as The Ancient One

Michael Stuhlbarg as Dr. Nicodemus West

Benjamin Bratt as Jonathan Pangborn

Scott Adkins as Lucian / Strong Zealot

Zara Phythian as Brunette Zealot

Alaa Safi as Tall Zealot

Katrina Durden as Blonde Zealot

Topo Wresniwiro as Hamir

Umit Ulgen as Sol Rama

Linda Louise Duan as Tina Minoru

Mark Anthony Brighton as Daniel Drumm

Meera Syal as Dr. Patel

Amy Landecker as Dr. Bruner

Adam Pelta-Pauls as Nurse Billy

Sarah Malin as Dr. Garrison

Eben Young as Dr. Weiss

Kobna Holdbrook-Smith as Physical Therapist

Elizabeth Healey as Concerned Doctor

Guillaume Faure as Reluctant Surgeon

Daniel Dow as Mugger

Stan Lee as Bus Passenger

Ezra Faroque Khan as Kamar-Taj Librarian

Kimberly Van Luin as Bullet Patient's Wife

Pat Kiernan as Pat Kiernan

Raj Awasti as Street Passerby (uncredited)

Jill Buchanan as Physio Patient (uncredited)

Daniel Eghan as Hospital Visitor (uncredited)

Juani Feliz as Girl on the Bus (uncredited)

Mo Idriss as New York Pedestrian (uncredited)

Tamika Katon-Donegal as Assistant (uncredited)

Pezh Maan as Doctor (uncredited)

Kei Miura as Hong Kong Officer (uncredited)

Cameron Moon as Sadhu (uncredited)

Emeson Nwolie as Man in Street (uncredited)

Clem So as Kamar-Taj Disciple (uncredited)

Chris Hemsworth as Thor (uncredited)

Samantha Russell as Apprentice (uncredited)