Johnny Depp as Frank Tupelo

Angelina Jolie as Elise Clifton-Ward

Paul Bettany as Inspector John Acheson

Timothy Dalton as Chief Inspector Jones

Steven Berkoff as Reginald Shaw

Rufus Sewell as The Englishman

Christian De Sica as Colonnello Lombardi

Alessio Boni as Sergente Cerato

Daniele Pecci as Tenente Narduzzi

Giovanni Guidelli as Tenente Tommassini

Raoul Bova as Conte Filippo Gaggia

Bruno Wolkowitch as Capitaine Courson

Julien Baumgartner as Brigadier Ricuort

François Vincentelli as Brigadier Marion

Clément Sibony as Brigadier Rousseau

Jean-Claude Adelin as Brigadier Cavillan

Jean-Marie Lamour as Cafe Waiter Jean-Michel

Nicolas Guillot as Cafe Head Waiter Jérôme

Mhamed Arezki as Courier Achmed Tchebali

Igor Jijikine as Virginsky

Vladimir Orlov as Lebyadkin

Vladimir Tevlovski as Liputin

Alec Utgoff as Fedka

Mark Zak as Shigalyov

Neri Marcorè as Hotel Concierge Alessio

Gabriele Gallinari as Hotel Bell Boy Luca

Riccardo De Torrebruna as Hotel Waiter Guido

Maurizio Casagrande as Waiter Antonio

Nino Frassica as Brigadiere Mele

Gwilym Lee as Senior Technician Mountain

Steven Robertson as Junior Technician Pinnock

Iddo Goldberg as Jones' Assistant Whitfield

Renato Scarpa as Arturo the Tailor

Giancarlo Previati as Gala Coordinator Dalla Pietà

Giovanni Esposito as Interpreter Coppa

Marino Narduzzi as Elise's Driver Stefano

Tino Giada as Elise's Driver Mauro

Bruno Bilotta as Sniper Chief Giordani

Ralf Moeller as Jail Bird Lunt

Marc Ruchmann as Brigadier Kaiser

Massimiliano Belsito as Dancer at Gala

Francesca Nerozzi as Dancer at Gala

Romina Carancini as Dancer at Gala

Jennifer Iacono as Dancer at Gala

Claudia Mancinelli as Dancer at Gala

Anoushka Rava as Woman in the Cafe (uncredited)