Brad Pitt as John Smith

Angelina Jolie as Jane Smith

Vince Vaughn as Eddie

Adam Brody as Benjamin Danz

Kerry Washington as Jasmine

Keith David as Father

Chris Weitz as Martin Coleman

Rachael Huntley as Suzy Coleman

Michelle Monaghan as Gwen

Stephanie March as Julie - Associate #1

Jennifer Morrison as Jade - Associate #2

Theresa Barrera as Janet - Associate #3

Perrey Reeves as Jessie - Associate #4

Melanie Tolbert as Jamie - Associate #5

Jerry T. Adams as Guard - Bull

Elijah Alexander as Marco Racin

Hans F. Alexander as Louis

Lauryn Alvarez as Coleman Kid #2

Burke Armstrong as Restaurant Patron

Ron Bottitta as P.J.

Earl H. Bullock as 50's Man

Miguel Angel Caballero as Bellboy - Bogotá

Victor A. Chapa as Americana Hotel Manager

Maree Cheatham as Father's Secretary

Laine Collins as Eddie's Waitress

Noah Dahl as Coleman Kid #1

Merrilee Dale as Mom #2

Chris Daniels as Mailman Assassin

Patrika Darbo as 50's Woman

Jennifer DeMille as Breakfast Diner Waitress

Tyce Diorio as Salsa Dancer #2

Patricia Donaldson as Louise

Sabi Dorr as Bodyguard #3

Greg Ellis as Mickey

David Escobedo as Americana Hotel Bartender

Kaela Freeman as Neighborhood Girl

Megan Gallagher as 40's Woman

Amy Hathaway as Beauty

Jessica Hedden as Hopskotch Girl #2

Kathrine Herzer as Hopscotch Girl #1

Nigel Hudson as Boxing Sparring Partner

Ravil Isyanov as Curtis

Stephanie Ittleson as Party Guest

Mark Ivanir as Patron - Dive Bar

Benton Jennings as Maitre'D

Simon Kinberg as Investment Banker #1

Peter Lavin as Leroy

Deren Tadlock as Doorman

Sean Mahon as Lucky

Kevin Makely as Johnson

Mike McCaul as Bill the Neighbor

Derek Medina as Policia #2

Will Moore as House Assassin #1

Joel Munoz as Policia #1

Mark Newsom as Guard #1

Richie Ornelas as Policia #4

Jordan Osher as House Assassin #2

Edward Padilla as Colombian Military Officer

Eugene C. Palmer as Judge

Luis Racer as Policia #3

Liz Ramos as Salsa Dancer #1

Leonard Robinson as Watchguard

Felix A. Ruiz as Vocalist

Sam Sabbah as Bodyguard

Kim Schioldan as Bartender - Dive Bar

Ty Sharp as Towncar Driver

Jimmy Shubert as Ancient Barker

Abigail Rose Solomon as Mom #3

Hannah Von Kanel as Hopskotch Girl #3

Ali Marsh as Mom #1

Kim H. Winther as Mr. Smith's Father

Michael Winther as Investment Banker #2

Michael-John Wolfe as Bartender - Coleman House

Jeff Yagher as 40's Man

Bryan Anthony as Dancer

Douglas Caldwell as Dancer

R.J. Durell as Dancer

Melissa Hurley as Dancer

Jacqui Landrum as Dancer

Carol Mack as Dancer

Michael Morris as Dancer

Gloria Rodriguez as Dancer

Linda Kathleen Taylor as Dancer

Anne Vardanian as Dancer

Ara Vardanian as Dancer

Luis Vasquez as Dancer

John W. Woodruff as Dancer

Angela Bassett as Mr. Smith's Boss (voice) (uncredited)

William Fichtner as Dr. Wexler - Marriage Counselor (voice) (uncredited)

David Block as Security Guard (uncredited)

John Branch as Swat Team Member (uncredited)

Julius Callahan as Sebastian James (uncredited)

Shilo Frontierro as Assassin (uncredited)

Lisa Gabriel as Dancer (uncredited)

Tony Longo as Big Bad Bathroom Dude (uncredited)

Janelle Marra as Woman #3 (uncredited)

Heather Petrone as BB Gun Shooter (uncredited)

Bill Viney as Dancer (uncredited)

Hawk Younkins as Swat Officer (uncredited)

Matt McColm as Assassin (uncredited)

Mo Gallini as Algerian Assassin (uncredited)