Albert Brooks as Steven Phillips

Sharon Stone as Sarah Little

Andie MacDowell as Laura Phillips

Jeff Bridges as Jack Warrick

Cybill Shepherd as Self

Monica Mikala as Julie Phillips

Jamie Alexis as Mary Phillips

Marnie Shelton as Jennifer

Catherine MacNeal as Anne

Mark Feuerstein as Josh Martin

Lorenzo Lamas as Lorenzo Lamas

Jennifer Tilly as Jennifer Tilly

Bradley Whitford as Hal

Skip O'Brien as Universal Studio Guard

Aude Charles as Spielberg Secretary #1

Ange Billman as Spielberg Secretary #2

Gannon Daniels as Spielberg Secretary #3

Jennie Ventriss as Older Secretary

Steven Wright as Stan Spielberg

Bobby Edner as Boy at Sarah's House

Stacey Travis as Phyllis

Michelle Crosby Jones as Tiffany Saleswoman

Paul C. Jenson as Four Seasons Porter

Steve Valentine as Four Seasons Assistant Manager

Greg Grunberg as Four Seasons Hotel Security

Rob Reiner as Rob Reiner

Alexandra Kaplan as Rob Reiner's Daughter

Steven Anthony Lawrence as Rob Reiner's Son

Wolfgang Puck as Wolfgang Puck

James Cameron as James Cameron

Jill Tobin as Female Attendant

Martin Scorsese as Martin Scorsese

Mario Opinato as European Man

Walter Williamson as Bruno

Dakin Matthews as Dr. Jacobson

Concetta Tomei as Nurse Rennert

A.J. Orta as Boy in Cookie Store

Greg Bronson as Hotel Doorman (uncredited)

Phil Hawn as Tiffany Patron (uncredited)