Shia LaBeouf as Sam Witwicky

Rosie Huntington-Whiteley as Carly

Peter Cullen as Optimus Prime (voice)

Leonard Nimoy as Sentinel Prime (voice)

John Turturro as Simmons

Frances McDormand as Mearing

Josh Duhamel as Lennox

Tyrese Gibson as Epps

Patrick Dempsey as Dylan

Hugo Weaving as Megatron (voice)

John Malkovich as Bruce Brazos

Kevin Dunn as Ron Witwicky

Julie White as Judy Witwicky

Alan Tudyk as Dutch

Ken Jeong as Jerry Wang

Glenn Morshower as General Morshower

Lester Speight as Eddie

Buzz Aldrin as Buzz Aldrin

Bill O'Reilly as Bill O'Reilly

Ravil Isyanov as Voshkod

Dustin Dennard as Lennox Lieutenant

Markiss McFadden as Lennox Team 'Baby Face'

Nick Bickle as Lennox Team 'Chapman'

Ajay James as Lennox Team 'Atroui'

Brett Lynch as Lennox Team 'Phelps'

Chris A. Robinson as Lennox Team 'Bruno'

Scott C. Roe as Lennox Team 'Nelson'

James D. Weston II as Lennox Team 'Tuens'

Brian Call as Lennox Team 'Taggart'

Aaron Garrido as Epps Team 'Mongo'

Mikal Vega as Epps Team 'Hooch'

Kenny Sheard as Epps Team 'Marc L'

Josh Kelly as Epps Team 'Stone'

Keiko Agena as Mearing's Aide

LaMonica Garrett as Morshower's Aide

Yasen Peyankov as Voshkod Associate

Brett Stimely as President Kennedy

John H. Tobin as President Nixon

Drew Pillsbury as Defense Secretary McNamara

Patrick Pankhurst as Director of NASA

Larry Clarke as NASA Scientist (1969)

Tom Virtue as Black Ops NASA Technician (1969)

Thomas Crawford as Black Ops NASA Technician (1969)

Kevin Sizemore as Black Ops NASA Technician (1969)

Alan Pietruszewski as NASA Mission Controller (1969)

Michael Daniel Cassady as NASA Launch Technician (1969)

Peter Murnik as Tracking Station Supervisor (1969)

Don Jeanes as Neil Armstrong (1969)

Cory Tucker as Buzz Aldrin (1969)

Lindsey Ginter as Old NASA Scientist

David St. James as Old NASA Scientist

Mitch Bromwell as NASA Technician

Elya Baskin as Cosmonaut Dimitri

Eugene Alper as Cosmonaut Yuri

Inna Korobkina as Russian Lady

Zoran Radanovich as Russian Bouncer

Kathleen Gati as Russian Female Bartender

Annie O'Donnell as Human Resources Lady

Chris Sheffield as Pimply Corporate Kid

Ken Takemoto as Japanese Executive

Michael Loeffelholz as Executive Interviewer

Mindy Sterling as Female Insurance Agent

Stephen Monroe Taylor as Mailroom Worker

Andy Daly as Mailroom Worker

Derek Miller as Mailroom Worker

Leidy Mazo as Mailroom Worker

Scott Krinsky as Accuretta Executive

Katherine Sigismund as Accuretta Worker

Maile Flanagan as Accuretta Worker

Darren O'Hare as Berated Scientist

Jack Axelrod as Simmons Tileman

Rich Hutchman as Engineer

Meredith Monroe as Engineer's Wife

Charlotte Labadie as Engineer's Daughter

Christian Baha as Dylan's Executive

Jennifer Williams as Dylan's Assistant

Danielle Fornarelli as Dylan's Assistant

Danny McCarthy as NEST Guard

John Turk as NEST Guard

Peter A Kelly as NEST Guard

Mark Golden as SEAL

Sean Murphy as SEAL

Scott Paulson as SEAL

Luis Echagarruga as SEAL

Iqbal Theba as UN Secretary General

Anthony Azizi as Lt. Sulimani

Sammy Sheik as Lt. Faraj

Mark Ryan as Military Drone Operator

John S. McAfee as GPS Tracking Coordinator

Jay Gates as DC Mall Reporter

Rebecca Cooper as DC Capitol Reporter

Jess Harnell as Ironhide (voice)

Charlie Adler as Starscream (voice)

Robert Foxworth as Ratchet (voice)

James Remar as Sideswipe (voice)

Francesco Quinn as Dino (voice)

George Coe as Que / Wheeljack (voice)

Tom Kenny as Wheelie (voice)

Reno Wilson as Brains (voice)

Frank Welker as Shockwave / Soundwave (voice)

Ron Bottitta as Roadbuster / Amp (voice)

John DiMaggio as Leadfoot / Target (voice)

Keith Szarabajka as Laserbeak (voice)

Greg Berg as Igor (voice)