James Garner as Wyatt Earp

Bruce Willis as Tom Mix

Malcolm McDowell as Alfie Alperin

Mariel Hemingway as Cheryl King

Kathleen Quinlan as Nancy Shoemaker

Jennifer Edwards as Victoria Alperin

Patricia Hodge as Christina Alperin

Richard Bradford as Captain Blackworth

M. Emmet Walsh as Chief Marvin Dibner

Joe Dallesandro as Dutch Kieffer

Andreas Katsulas as Arthur

Dann Florek as Marty Goldberg

Bill Marcus as Hal Flynn

Michael C. Gwynne as Mooch

Dermot Mulroney as Michael Alperin

Miranda Garrison as Spanish Dancer

Liz Torres as Rosa

Castulo Guerra as Pancho (as Cástulo Guerra)

Dakin Matthews as William Singer

Vernon Wells as Australian Houseman

Dennis Rucker as Paul

John Dennis Johnston as Ed

Kenny Call as Cowboy Fred

Jack Garner as Cowboy Henry

Jerry Tullos as Leo Vogel

Herb Tanney as George the Conductor (as Steem Tanney)

Peter Jason as Frank Coe

Richard Fancy as Academy Speaker

Glenn Shadix as Roscoe Arbuckle

Lisa Alpert as Michael's Secretary

Sonia Zimmer as Dibner's Secretary

Marina Palmier as Candy Store Girl

Tessa Taylor as Candy Store Girl

Jon Van Ness as Director

P. Randall Bowers as Assistant Director (as Randy Bowers)

Maureen Teefy as Stagecoach Lady

Arnold Johnson as George

Eric Harrison as Alperin Butler

Amy Michelson as Alfie's 1st Wife

James O'Connell as Gate Guard

Bing Russell as Studio Guard

James C. Lewis as Jail Guard (as C. James Lewis)

William Applegate Jr. as Jail Inmate (as Bill Applegate)

Luis Contreras as Jail Inmates

Charles Noland as Jail Inmates

Robert Covarrubias as Jail Inmates

Donalin Patton as Girls at Lunch

Kay Perry as Girls at Lunch

Rod McCary as Douglas Fairbanks

John Fountain as John Gilbert

Irene Olga López as Asuncion Maria Romero (as Irene Olga Lopez)

Jeris Poindexter as Cleaning Man

F. William Parker as Mayor Robert Hellman

Grant Heslov as Car Attendant

Don Sparks as Reporters

Melanie Jones as Reporters

Darrah Meeley as Reporters

Tom Tarpey as Reporters

Krista Gray as Reporters

Katie Morgan as Reporters

Bevis Faversham as Oliver Hardy (uncredited)

Paul Higby as Newspaper Reporter (uncredited)

Vincent Jerman-Jerosa as James Cagney (uncredited)

Beverly Leech as Thelma Todd (uncredited)

Marilyn Michaels as Mae West lookalike / Candy Girl (uncredited)

Denney Pierce as Billy Clanton (uncredited)

Barry Vigon as Boat Captain (uncredited)