Lake Bell as Alice Brewing

Ed Helms as Noah Brewing

Mary Steenburgen as Cybil Burger

Paul Reiser as Harvey Burger

Amber Heard as Fanny

Wyatt Cenac as Zander

Dolly Wells as Vivian Prudeck

Chace Crawford as Egon

Rae Gray as Lyn

Beth Grant as Phyllis

Marcanthonee Reis as Zenith

Sky Elobar as Scotty

Heath McGough as Willy

Connie Shin as Mel

Hannah Friedman as Milly

Zac Scheinbaum as Quilton

Susan James Berger as Newly Hopeful Addict

Chauntae Pink as Bonnie

Diane Dehn as Wife

Miranda Bailey as Local Reporter

Jeremy A. Lopez as Husband