Shirley MacLaine as Harriet Lauler

Amanda Seyfried as Anne Sherman

Anne Heche as Elizabeth

Thomas Sadoski as Robin Sands

Philip Baker Hall as Edward

Adina Porter as Bree Wilson

Sarah Baker as Zoe

Tom Everett Scott as Ronald Odom

Gedde Watanabe as Louie the gardener

Joel Murray as Joe Mueller

Marshall Bell as Edward

Steven Culp as Sam Serman

Basil Hoffman as Christopher Georrge

Nikki McCauley as Dawn DJ

Valeri Ross as Wanda Byers

Alanna Ubach as Toby

AnnJewel Lee Dixon as Brenda

Marcy Jarreau as Focus Group Woman #1

Brooke Trantor as Focus Group Woman #2

Joshua Harto as Focus Group Man 1

Yvette Freeman as Housekeeper

Todd Louiso as Dr. Morgan

Chloé Wepper as Agency Receptionist

Jesse Burch as Moderator

Natalija Nogulich as Middle Aged Woman

Bill Glass as Father Piper

Millicent Martin as Margaret Dumont

John Billingsley as Father Reilly

James Tupper as Man at Funeral (uncredited)

Nicole Fazio as Waitress (uncredited)

Juan Jose Dubon as Radio Station Intern Worker (uncredited)

J. Denise as Radio Station Employee (uncredited)