Tom Kenny as SpongeBob SquarePants / Gary the Snail (voice)

Bill Fagerbakke as Patrick Star (voice)

Rodger Bumpass as Squidward Tentacles (voice)

Mr. Lawrence as Plankton (voice)

Keanu Reeves as Sage

Clancy Brown as Mr. Krabs (voice)

Carolyn Lawrence as Sandy Cheeks (voice)

Matt Berry as King Poseidon (voice)

Jill Talley as Karen (voice)

Mary Jo Catlett as Mrs. Puff (voice)

Awkwafina as Otto (voice)

Snoop Dogg as The Gambler

Danny Trejo as El Diablo

Tiffany Haddish as Master of Ceremonies (voice)

Reggie Watts as Chancellor (voice)

Antonio Raul Garcia as Young SpongeBob (voice)

Jack Gore as Young Patrick (voice)

Jason Maybaum as Young Squidward (voice)

Presley Williams as Young Sandy (voice)

Dee Bradley Baker as Perch Perkins (voice)