Blu Hunt as Dani Moonstar

Maisie Williams as Rahne Sinclair

Anya Taylor-Joy as Illyana Rasputin

Charlie Heaton as Samuel Guthrie

Henry Zaga as Roberto da Costa

Alice Braga as Dr. Reyes

Adam Beach as Dani's Father

Happy Anderson as Reverend Craig

Dustin Ceithamer as Smiling Man

Marilyn Manson as Smiling Man (voice)

Thomas Kee as Sam's Father

Colbi Gannett as Young Illyana

Jacinto Vega SpiritWolf as Frozen Cheyenne

Mickey Gilmore as Coal Miner (uncredited)

Jeffrey Corazzini as Coal Miner (uncredited)