Kim Coates as Officer Downe

Luna Lauren Velez as Police Chief Berringer

Sona Eyambe as Zen Master Flash

Reno Wilson as Officer Carter

Bruno Gunn as Officer Fritch

Tracy Vilar as Officer Hanso

Meadow Williams as Mother Supreme

Shawn Crahan as Lion

Lindsay Pulsipher as Miss Tiger

Chris Fehn as Vulture

Corey Taylor as Headcase Harry

Alison Lohman as Nun

Cody Renee Cameron as Naked Woman

Sam Witwer as Burnham

Ankur Bhatt as Lab Tech #1

J. J. Soria as Lab Tech #2

Jarvis W. George as Police Sgt.

Mark Neveldine as Hazmat #1 (Johnny)

Cory Brennan as Hazmat #2

Skip Williamson as Hazmat #3

Glenn Howerton as Dominic

Jun Hee Lee as Fortune 500 Aide

Erich Anderson as Bartender

Tully Banta-Cain as Inmate #1

Nick Nicotera as Drunk Cop

Sid Wilson as Crook #1

Adi Shankar as Crook #2

Kaylee Sapieha as Evelyn Schwarzenhoffer

Phil Morris as Zen Master Flash (English Dub) (voice)

Jai Stefan as

J.B. Abajian as Telekinetic (uncredited)

Emilia Bogdanova as Nun

Tamiko Brownlee as Zen Student

Shad Gaspard as Brick

Jackson George as Inmate #7

Ximena Maria Iacono as Waitress

Lisbeth Kingsley as Zen Student

Constance Steele as Blood Girl / Officer Downe's Wife

Mallory Thompson as Nun