Demetrius Shipp Jr. as Tupac Shakur

Danai Gurira as Afeni Shakur

Kat Graham as Jada Pinkett

Jamal Woolard as Biggie Smalls

Dominic L. Santana as Suge Knight

Annie Ilonzeh as Kidada Jones

Lauren Cohan as Leila Steinberg

Cory Hardrict as Haitian Jack

Grace Gibson as Faith Evans

DeSean Jackson as Street Entrepreneur

Brandon Sauve as Ted Field

Josh Ventura as Tom Whalley

Azad Arnaud as Daz

Sean Baker as Big B

Harold 'House' Moore as Dr. Dre

Khadija Copeland as Queen Latifah

Chanel Young as Aunt Linda

Chris Clarke as Shock G.

Money-B as Money B.

Hamid-Reza Benjamin Thompson as Ronnie

DeRay Davis as Legs

Bruce Davis as Black C.O.

Keith D. Robinson as Atron

Gary Weeks as Attorney

Jarrett Ellis as Snoop Dogg

Clifton Powell as Floyd

Rayven Symone Ferrell as Set

Scott Hunter as Scott Whitwell

Johnell Young as Ray Luv (uncredited)

Rayan Lawrence as Treach (uncredited)

Sheril Rodgers as Mall Patron (uncredited)