Bette Midler as Mother Earth

Michael Keaton as Charles McIntyre

Morgan Freeman as Walter Samson

Martin Short as Nathan Thurm

Geena Davis as Kim

Jane Fonda as Hellen

Rhea Perlman as Paula

Danny DeVito as Vic

Dan Aykroyd as Vic's Buddy

Chevy Chase as Vic's Buddy

Rick Moranis as Vic's Buddy

Jack Lemmon as Coach Stewart

Kevin Costner as Bartender

James Brolin as Doctor

Dana Delany as Doctor

Edward James Olmos as Hospital Director

Dustin Hoffman as Every Lawyer

Robin Williams as Everyman

Meryl Streep as Concerned Citizen

Dennis Miller as Weekend Update Anchor

Candice Bergen as Murphy Brown

Harold Ramis as Elon Spengler

Christopher Lloyd as Dr. Emmett L. Brown

Neil Patrick Harris as Doogie Howser M.D.

Rodney Dangerfield as Dr. Vinny Boombatz

Ted Danson as Sam Malone

Kirstie Alley as Rebecca Howe

Woody Harrelson as Woody Boyd

George Wendt as Norm Peterson

John Ratzenberger as Cliff Clavin

Kelsey Grammer as Dr. Frasier Crane

Bill Cosby as Dr. Cliff Huxtable

Phylicia Rashād as Clair Huxtable

Lisa Bonet as Denise Huxtable

Malcolm-Jamal Warner as Theo Huxtable

Tempestt Bledsoe as Vanessa Huxtable

Keshia Knight Pulliam as Rudy Huxtable

Raven-Symoné as Olivia Kendall

Will Smith as Fresh Prince

Bea Arthur as Dorothy Zbornak

Betty White as Rose Nylund

Rue McClanahan as Blanche Devereaux

Estelle Getty as Sophia Petrillo

Ed O'Neill as Al Bundy

Katey Sagal as Peggy Bundy

Christina Applegate as Kelly Bundy

David Faustino as Bud Bundy

Amanda Bearse as Marcy D'Arcy

Downtown Julie Brown as Self

Christopher Reid as Kid [Kid 'N Play]

Christopher Martin as Play [Kid 'N Play]

Jeff Bergman as Bugs Bunny / Porky Pig / Tweety (voice)

Jim Henson as Kermit the Frog (voice)

Jerry Nelson as Robin the Frog (voice)

Dave Goelz as Old Frog (voice)

Richard Hunt as Crocodile (voice)

David Rudman as Lizard (voice)

Kevin Clash as Additional Muppets (voice)

Steve Whitmire as Additional Muppets (voice)

Rick Ducommun as Guard

Mayim Bialik as Self

Michael Douglas as Self

Heavy D as Self

Ice-T as Self

Magic Johnson as Self

Quincy Jones as Self

Melanie Mayron as Self

Queen Latifah as Self

Pat Riley as Self

Carl Sagan as Self

Barbra Streisand as Self

Tone Loc as Self

Alex Trebek as Self

Jonathan Brandis as Self

Dan Gauthier as Self

Edan Gross as Self

Dom Irrera as Self

Jim Lange as Self

Robert Wuhl as Self

Rickey Boyd as Self (uncredited)

Danny 'Budman' Delany as Self (uncredited)

Michael Gio Ferrigno as Self (uncredited)

Peter Horton as Self (uncredited)

Bruce Weitz as Self (uncredited)

Don Pardo as Weekend Update Announcer (voice) (uncredited)