Lionel Barrymore as Julian Northrup aka Gramps

Cedric Hardwicke as Mr. Brink

Beulah Bondi as Nellie Northrup aka Granny

Una Merkel as Marcia Giles

Bobs Watson as Pud Northrup

Nat Pendleton as Mr. Grimes

Henry Travers as Dr. Evans

Grant Mitchell as Mr. Pilbeam

Eily Malyon as Demetria Riffle

James Burke as Sheriff Burlingame

Charles Waldron as Reverend Murdock

Ian Wolfe as Charles Wentworth

Phillip Terry as Bill Lowry

Truman Bradley as James Northrup

Dorothy Adams as Florist (uncredited)

Barbara Bedford as Mrs. James Northrup (uncredited)

Sonny Bupp as Boy in Tree (uncredited)

Hans Conried as Man in Convertible (uncredited)

Howard Hickman as Chief Surgeon (uncredited)

Dickie Jones as Boy in Tree (uncredited)

George Lloyd as Chief of Police (uncredited)

Ted Oliver as State Trooper (uncredited)

Doris Rankin as Mrs. Burlingame (uncredited)

Harold Schlickenmayer as First Stretcher Bearer (uncredited)