Uma Thurman as The Bride / Beatrix Kiddo (Black Mamba) / Mommy

Lucy Liu as O-Ren Ishii (Cottonmouth)

Vivica A. Fox as Vernita Green (Copperhead)

Michael Madsen as Budd (Sidewinder)

Daryl Hannah as Elle Driver (California Mountain Snake)

David Carradine as Bill (Snake Charmer)

Sonny Chiba as Hattori Hanzo

Julie Dreyfus as Sofie Fatale

Chiaki Kuriyama as Gogo Yubari

Gordon Liu Chia-Hui as Johnny Mo / Pai Mei

Michael Parks as Earl McGraw / Esteban Vihaio

Ambrosia Kelley as Nikki Bell

Michael Bowen as Buck

Jun Kunimura as Boss Tanaka

Kenji Ohba as Bald Guy

Yuki Kazamatsuri as Proprietor

Sakichi Sato as Charlie Brown

Jonathan Loughran as Trucker

Yoshiyuki Morishita as Tokyo Businessman

Tetsuro Shimaguchi as Crazy 88 #1 (Miki)

James Parks as Edgar McGraw

Kazuki Kitamura as Crazy 88 #2 / Boss Koji

Yoji Tanaka as Crazy 88 #3

Issey Takahashi as Crazy 88 #4

Sō Yamanaka as Crazy 88 #5

Juri Manase as Crazy 88 #6 (Girl)

Akaji Maro as Boss Ozawah

Goro Daimon as Boss Honda

Shun Sugata as Boss Benta

Zhang Jinzhan as Boss Orgami

Hu Xiaohui as Young 88 (Spanked Boy)

Sachiko Fujii as The 5, 6, 7, 8’s

Yoshiko Yamaguchi as The 5, 6, 7, 8’s

Ronnie Yoshiko Fujiyama as The 5, 6, 7, 8’s

Shu Lan Tuan as Okinawa Airline Ticket Agent

Ai Maeda as O-Ren (anime sequence) (voice)

Naomi Kusumi as Boss Matsumoto (anime sequence) (voice)

Hikaru Midorikawa as Pretty Riki (anime sequence) (voice)

Perla Haney-Jardine as B.B.

Larry Bishop as Larry Gomez

Samuel L. Jackson as Rufus

Christopher Allen Nelson as Tommy Plympton

Helen Kim as Karen Kim

Laura Cayouette as Rocket

Claire Smithies as Clarita

Sid Haig as Jay (Bartender)

Bo Svenson as Reverend Harmony

Jeannie Epper as Mrs. Harmony

Stephanie L. Moore as Joleen

Shana Stein as Erica

Caitlin Keats as Janeen

Reda Beebe as Lucky

Clark Middleton as Ernie

Victoria Lucai as Trixie

Venessia Valentino as 1st Grade Teacher

Thea Rose as Melanie Harrhouse

William Paul Clark as Soda Jerk

Stevo Polyi as Tim

Al Manuel Douglas as Marty Kitrosser

Patricia Silva as Hooker #1

Maria Del Rosario Gutierrez as Hooker #2

Sonia Angelica Padilla Curiel as Hooker #3

Veronica Janet Martinez as Hooker #4

Lucia Cruz Marroquin as Hooker #5

Citlati Guadalupe Bojorquez as Hooker #6

Graciela Salazar Mendoza as Hooker #7

Maria de Lourdes Lombera as Hooker #8

Jorge Silva as Bartender/Pimp