Mary McDonnell as May-Alice Culhane

Alfre Woodard as Chantelle

Vondie Curtis-Hall as Sugar LeDoux

David Strathairn as Rennie

Leo Burmester as Reeves

Nora Dunn as Ti-Marie

Mary Portser as Precious

Angela Bassett as Rhonda / Dawn

Sheila Kelley as Kim

Nancy Mette as Nina

Lenore Banks as Nurse Quick

Will Mahoney as Max

Nelle Stokes as Therapist #1

Brett Ardoin as Therapist #2

Michael Mantell as Dr. Kline

Daniel Dupont as Therapist #3

Chuck Cain as Attendant

Shana Ledet Qualls as Fan #1

Paula Lafleur as Fan #2

Maggie Renzi as Louise

Marianne Muellerleile as Drushka

Victoria Edwards as Jessica

Amanda Carlin as Perky

Elaine West as Phoebe

Linda Castle as Lawanda

Leigh 'Little Queenie' Harris as Kit

Tom Wright as Luther

Jennifer Gardner as Albertine

Shauntisa Willis as Denita

John Henry Redwood as Denita

Michael Laskin as Redwood Vance

John Sayles as Soap Opera Doctor (uncredited)