Keke Palmer as Wednesday

Haley Ramm as Nikki

Edi Gathegi as Kenny Wayne

Aunjanue Ellis-Taylor as Gloria May

Vanessa Morgan as Destiny

DMX as Midnight John

Paige Searcy as Charlie

Tarik Lowe as Baby Love

Lyrica Okano as Kim

Kaitlyn Bausch as Blondie

Rayan Lawrence as Jamal

Calvin Dutton as Malcolm

Paola Lázaro as Louisa

Taliyah Whitaker as Young Wednesday

Chloe Rayne Watson as Young Nikki

David Hennessey as Ray

Monette McKay as Sweetheart

Tess Strohm as Nina