Riccardo Scamarcio as Renato De Pedis

Maya Sansa as Maria

Greta Scarano as Sabrina Minardi

Valentina Lodovini as Raffaella Notariale

Shel Shapiro as John

Adriana Serrapica as Emanuela Orlandi

Pietro Orlandi as se stesso

Tommaso Lazotti as autore "Chi l'ha visto?"

Simone Coppo as prelato assistente di Paul Marcinkus

Luciano Roffi as Lio Beghin, l'autore di "Chi l'ha visto?"

Anthony Souter as Roberto Calvi

Randall Paul as arcivescovo Paul Marcinkus

Elettra Orlandi as Federica Orlandi

Mino Caprio as prelato

Alberto Cracco as prelato

Alessandro Bertolucci as Ercole Orlandi

Sandro Stefanini as Don Pietro Vergari

Laura De Marchi as Suor Dolores