Barbara Hershey as Aunt Julia

Keanu Reeves as Martin Loader

Peter Falk as Pedro Carmichael

Bill McCutcheon as Puddler

Patricia Clarkson as Aunt Olga

Richard Portnow as Uncle Luke

Jerome Dempsey as Sam & Sid

Richard B. Shull as Leonard Pando

Paul Austin as Donald Loader

Joel Fabiani as Ted Orson

Crystal Field as Josephine Sanders

Jayne Haynes as Aunt Hortensia

Mary Joy as Frances Loader

Rob Kramer as Jamie

Anna Thomson as Faith Hope

Peter Maloney as Luther Aslinger

Irving Metzman as Producer Detroit Radio

Bill Moor as Duke Vermont

Dedee Pfeiffer as Nellie

Jon Van Ness as Brent Moconnochie

William Murray Weiss as Peter Loader

Henry Gibson as Big John Coot

Peter Gallagher as Richard Quince

Dan Hedaya as Robert Quince

Buck Henry as Father Serafim

Hope Lange as Margaret Quince

John Larroquette as Doctor Albert Quince

Elizabeth McGovern as Elena Quince

Robert Sedgwick as Elmore Dubarque

Danny Aiello III as Large Albanian Man #2

Pawl Burke as Albanian Protester

Jack Harvey as Fireman

Mert Hatfield as WXBU Engineer

Shirley Horn as Jazz Singer

Ishmond Jones as Waiter

Howard Kingkade as News Man Detroit

Adam LeFevre as Large Albanian Man

Chuck Margiotta as Large Albanian Man #3

Ray McKinnon as Cub Reporter

Gladys Vega as Secretary

Jack Wallace as Policeman

Wynton Marsalis as The Wynton Marsalis Band

Wessell Anderson as The Wynton Marsalis Band

Wycliffe Gordon as The Wynton Marsalis Band

Herlin Riley as The Wynton Marsalis Band

Marcus Roberts as The Wynton Marsalis Band

Reginald Veal as The Wynton Marsalis Band

Michael White as The Wynton Marsalis Band

Todd Williams as The Wynton Marsalis Band

Aaron Neville as The Neville Brothers

Art Neville as The Neville Brothers

Charles Neville as The Neville Brothers

Cyril Neville as The Neville Brothers

Curtis Lambert as Copy Boy (uncredited)

Robert J. Maxwell as Albanian Demonstrator (uncredited)

Patt Noday as Smooching Jazz Club Guest (uncredited)