Brad Pitt as Roy McBride

Tommy Lee Jones as H. Clifford McBride

Liv Tyler as Eve

Ruth Negga as Helen Lantos

Donald Sutherland as Thomas Pruitt

Kimberly Elise as Lorraine Deavers

Loren Dean as Donald Stanford

Donnie Keshawarz as Captain Lawrence Tanner

Sean Blakemore as Willie Levant

Bobby Nish as Franklin Yoshida

LisaGay Hamilton as Adjutant General Vogel

John Finn as Brigadier General Stroud

John Ortiz as Lieutenant General Rivas

Freda Foh Shen as Captain Lu

Kayla Adams as Female Flight Attendant

Ravi Kapoor as Arjun Dhariwal

Elisa Perry as Woman in White Pants/Shirt

Daniel Sauli as Sal

Kimmy Shields as Sergeant Romano

Kunal Dudheker as Technician One

Greg Bryk as Chip Garnes

Alyson Reed as Janice Collins

Sasha Compère as Female Team Member

Justin Dray as Male Team Member

Alexandria Rousset as Woman on Screen

Natasha Lyonne as Tanya Pincus

Zoro Saro Manuel Daghlian as SPACECOM Employee

Jacob Sandler as Young Roy

Elizabeth Willaman as Cepheus (voice)

Robert J. Yowell as Lunar Base Technician (uncredited)

Nicholas Walker as Lunar Medic (uncredited)

Amanda Tudesco as Grace (uncredited)

Brynn Route as Shunga Hologram (uncredited)

Valeri Ross as Moon TV Guest #1 (uncredited)

Rochelle Rose as BBC News Reporter (uncredited)

Eloy Perez as Lt. Nash (uncredited)

Melvin Payne Jr. as Russian Astronaut (uncredited)

Jean-Pierre Mouzon as American Astronaut (uncredited)

Jen Morillo as Hologram Dancer (uncredited)

Noelle Messier as Capt. Devries (uncredited)

Anne McDaniels as Shunga Hologram (uncredited)

Kento Matsunami as Hip Japanese Traveler (uncredited)

Mallory Low as Spacecom Employee (uncredited)

Sheila M. Lockhart as Drug Addict (uncredited)

Donna Lee as Hip Japanese Traveler (uncredited)

Halszka Kuza as Dancer (uncredited)

Bayani Ison as Asian Male Host (uncredited)

Danny Hamouie as Rory Flynn (uncredited)

Georgia James Gray as Evelyn McBride (uncredited)

Eleanor Goodall as Ship Med Tech (uncredited)

Luis Richard Gomez as Jim (uncredited)

Eliza Gerontakis as The Singing Face (uncredited)

Vivian Fleming-Alvarez as Mars Officer Daniels (uncredited)

Lawrence Dex as Robert (uncredited)

Bayardo De Murguia as Hector Bustamante (uncredited)

Rodney Damon Collins as Mechanic (uncredited)