Sylvester Stallone as John Rambo

Paz Vega as Carmen

Sergio Peris-Mencheta as Hugo Martínez

Adriana Barraza as María Beltrán

Yvette Monreal as Gabriela

Joaquín Cosío as Don Manuel

Pascacio López as 'El Flaco'

Óscar Jaenada as Víctor Martínez

Nicholas Wittman as Male Hiker

Jessica Madsen as Becky

Louis Mandylor as Sheriff

Fenessa Pineda as Gizelle

Marco de la O as Manuel

Álvaro Flores as Cartel Man

Úrsula Murayama as Manuel's Wife

Atanas Srebrev as American Merc

Rick Zingale as Don Miguel

David Aguirre Firth as 'Padrote'

Díana Bermudez as Experienced Girl

Victor Baioco as Mex Sicario #10

Dimitri 'Vegas' Thivaios as Bouncer

Alexander Dimitrov as Heli Pilot

Genie Kim as Bar Patron

Aaron Cohen as State Police Captain

Owen Davis as Rescue Worker

Jamieson Urquhart as Young Man (Party) #1

Brayden Pindur as Young Man (Pilot) #2

Cathy Pulido as 'El Flaco' Bar Girl

Manuel Uriza as Doctor Sergio

Georgi Manchev as Deputy #1

Mirka Prieto as Lola / Laura

Cuco Usín as Fat Policeman

Domenic Charles Vargas as Mex Sicario #7

Sheila Shah as Alejandra

Simona Zdravkova as Brothel Girl

Tanya Stefanova as Brothel Girl

Velichka Georgieva as Brothel Girl

Dobrinka Georgieva as Brothel Girl

Ashli Dolat as Security House Girl

Gloria Georgieva as Security House Girl

Melani Petrova as Security House Girl

Nadejda Koleva as Security House Girl

Simona Yanusheva as Security House Girl

Jaklin as Security House Girl

Melin Edrinch as Security House Girl

Roza Georgieva as Security House Girl

Madlen Kovacheva as Security House Girl

Evelina Igova as Experienced Girl

Daniel Mora as Helicopter Pilot

Lyubomir Neykov as White Man Brothel

Georgi Dimitrov as Deputy #2