Steve Carell as Larry 'Doc' Shepherd

Bryan Cranston as Sal Nealon

Laurence Fishburne as Reverend Richard Mueller

J. Quinton Johnson as Charlie Washington

Deanna Reed-Foster as Ruth Mueller

Yul Vazquez as Lieutenant Colonel Wilits

Graham Wolfe as John Redman

Jeff Monahan as O'Toole

Dontez James as DAFB Guard

Tammy Tsai as Mother (Irene)

Richard Barlow as Angry Father

Cathy O'Dell as Grieving Mother

Jane Mowder as Rental Truck Employee

Richard Robichaux as Anorak

Jerry Lee Tucker as Raincoat

Marc Moore as Hyped-up Employee

Kate Easton as Phone Shop Clerk

Cicely Tyson as Mrs. Hightower

Sarah Silk as Front Desk Motel Employee

Ted Watts Jr. as Leland

Lee Harrington as Jamie

Samuel Davis as Larry Jr. (voice)

Brian 'Wolfman Black' Bowman as Church Member (uncredited)

Kelli Culbertson as Bar Patron (uncredited)

Chris Dettone as Train Passenger (uncredited)

Chris Drexel as Bar Patron (uncredited)

Eric Frank as Bar Patron Guy in Booth (uncredited)

Adam Hicks as Marine (uncredited)

John W. Iwanonkiw as J Tinsley Amtrak Baggage Handler (uncredited)

Trudi Kennedy as Train Passenger (uncredited)

Daniel Lamont as Bar Patron (uncredited)

James Lloyd as Bar Patron (uncredited)

Christopher Nardizzi as Train Passenger (uncredited)

Phil Nardozzi as Bus Passenger (uncredited)

Rebecca Phipps as Mourner (uncredited)

Dwayne Pintoff as Train Passenger (uncredited)

Sofia Plass as Church Member (uncredited)

Eric Rasmussen as Driver (uncredited)

Mario Ruiz as Senior Airman Morris (uncredited)

Brian E Stead as Amtrak Passenger (uncredited)

Gary Lee Vincent as Train Passenger (uncredited)

Jeremy Waltman as Train Passenger (uncredited)

Zoe Xandra as Funeral Attendee (uncredited)

Daniel James as Cellphone Store Patron (uncredited)

Wain Jenkins as Choir Member (uncredited)