John Wayne as Breck Coleman

Marguerite Churchill as Ruth Cameron

El Brendel as Gus

Tully Marshall as Zeke

Tyrone Power Sr. as Red Flack

David Rollins as Dave Cameron

Frederick Burton as Pa Bascom

Ian Keith as Bill Thorpe

Charles Stevens as López

Louise Carver as Gus' Mother-in-law

Victor Adamson as Wagon Train Man

Phyllis Bainbridge as Pioneer

Chief John Big Tree as Indian

Ward Bond as Sid Bascom

Nora Bush as Pioneer

Martin Cichy as Pioneer

Don Coleman as Wrangler

Nancy Crowley as Pioneer Child

Curley Dresden as Pioneer

Adabelle Driver as Pioneer

Emslie Emerson as Sairey

Alphonse Ethier as Marshal

Theresa Garon as Pioneer

William Gillis as Pioneer

Dannie Mac Grant as Pioneer Boy

Virginia Griffith as Pioneer

Marcia Harris as Mrs. Riggs

Marilyn Harris as Pioneer Girl

Al Haskell as Pioneer

DeWitt Jennings as Boat Captain Hollister

Jack Kenny as Pioneer

Bert Keys as Pioneer

John Lawrence Kneedy as Wagon Driver

Ann Kunde as Pioneer

Marjorie Leet as Mildred Riggs

Marion Lessing as Pioneer Girl

Frances Martinson as Pioneer

Frank McGrath as Pioneer

William V. Mong as Wellmore

Pete Morrison as Wrangler

Beth Nagel as Pioneer

Dodo Newton as Abigail Vance

Artie Ortego as Pioneer

Jack Padjan as Pioneer

Helen Parrish as Honey Girl Cameron

Robert Parrish as Pioneer Boy

Harvey Parry as Pioneer

Jack Peabody as Bill Gillis

Russ Powell as Windy Bill

Frank Rainboth as Ohio Man

Apache Bill Russell as Indian Scout

Lucile Sewall as Pioneer

Andy Shuford as Ohio Man's Son

Tom Smith as Pioneer

Jean Stoddard as Pioneer

Gertrude Van Lent as Sister from Missouri

Lucille Van Lent as Sister from Missouri