John Wayne as Capt. Kirby York

Henry Fonda as Lt. Col. Owen Thursday

Shirley Temple as Philadelphia Thursday

Pedro Armendáriz as Sgt. Beaufort

Ward Bond as Sgt. Maj. Michael O'Rourke

George O'Brien as Capt. Sam Collingwood

Victor McLaglen as Sgt. Festus Mulcahy

Anna Lee as Mrs. Emily Collingwood

Irene Rich as Mrs. Mary O'Rourke

Dick Foran as Sgt. Quincannon

Guy Kibbee as Capt. Dr. Wilkens

Grant Withers as Silas Meacham

Jack Pennick as Sgt. Daniel Schattuck

Ray Hyke as Lt. Gates

Movita as Guadalupe

Miguel Inclán as Cochise

Mary Gordon as Ma (barmaid)

Philip Kieffer as Cavalryman

Mae Marsh as Mrs. Gates

Hank Worden as Southern Recruit

John Agar as 2nd Lt. Michael Shannon O'Rourke

Abdullah Abbas as Officer at Dance (uncredited)

Danny Borzage as Recruit With Mustache / Accordionist at Serenade (uncredited)

Cliff Clark as Stage Driver (uncredited)

Jane Crowley as Officer's Wife (uncredited)

Frank Ferguson as Newspaperman (uncredited)

Francis Ford as Fen - Stage Guard (uncredited)

William Forrest as Reporter (uncredited)

Fred Graham as Cavalryman (uncredited)

Frank McGrath as Cpl. Derice (uncredited)

Clyde McLeod as Officer at Dance (uncredited)

Russell Meeker as Officer at Dance (uncredited)

Al Murphy as Orchestra Leader (uncredited)

John Rice as Officer at Dance (uncredited)

Phil Schumacher as Soldier (uncredited)

Allen D. Sewall as Officer at Dance (uncredited)

Mickey Simpson as NCO at Dance (uncredited)

Leslie Sketchley as Officer at Dance (uncredited)

Brick Sullivan as Officer at Dance (uncredited)

Harry Tenbrook as Tom O'Feeney (uncredited)

Archie Twitchell as Reporter (uncredited)

Eleanore Vogel as Officer's Wife (uncredited)