Keir Gilchrist as Craig Gilner

Emma Roberts as Noelle

Zach Galifianakis as Bobby

Viola Davis as Dr. Eden Minerva

Lauren Graham as Lynn Gilner

Jim Gaffigan as George Gilner

Jeremy Davies as Smitty

Zoë Kravitz as Nia

Bernard White as Muqtada

Thomas Mann as Aaron Fitzcarraldo

Matthew Maher as Humble

Adrian Martinez as Johnny

Aasif Mandvi as Dr. Mahmoud

Dana DeVestern as Alyssa Gilner

Karen Chilton as Nurse Harper

Rosalyn Coleman as Monica

Daniel London as Solomon

Leo Allen as Mr. Reynolds

Morgan Murphy as Joanie

Billy McFadden as Little Craig

Jared Goldstein as Ronny

Alan Aisenberg as Scuggs

Lou Myers as Jimmy

MacIntyre Dixon as Roger

Molly Hager as Becca

Ato Blankson-Wood as Jennifer

Ben Folstein as Neil

Stewart Steinberg as Charlie

Roddy Skeaping as