Sander Vanocur as Self

Jane Kaczmarek as Dr. Caroline Jaffe

Bree Walker as Self

Dwier Brown as Matt Jensen

Brian McNamara as Mike Curtis

James Morrison as Paul Whitaker

Ashley Peldon as Kimberly Hastings

James Handy as Dr. Norbert Hazelton

Kario Salem as Dr. Avram Mandel

Spencer Garrett as Paul Collingwood

Gina Hecht as Barbara Shiller

John de Lancie as Barry Steinbrenner

Patty Toy as Denise Wong

Dennis Lipscomb as Dr. Richard Pearson

Ron Canada as Terrance Freeman

Victor Wilson as Mark Manetti

Philip Baker Hall as Dr. Kurt Lowden

Jim Pirri as Robert Marino

Alan Scarfe as General Lucian Alexander

Cynthia Allison as Self

Ernie Anastos as Self

Arthur C. Clarke as Self

Sandy Hill as Self

Michelle Holden as Self

Mario Machado as Self

Warren Olney as Self

Saida Pagan as Self

Richard Saxton as Self

Debra Snell as Self

Randy Crowder as Deputy Anton Peters

Diana Frank as Sylvie Chounard

Marnie McPhail as Donna Hastings

Sherri Paysinger as Pamela Barnes

Robert Peters as Dwayne Haskell

Lou Beatty Jr. as Dr. Jonas Tremblay

Frank Bruynbroek as French Skier

John DeMita as Major Powers

Tyler Cole Malinger as Tyler O’Neal

Marnie Mosiman as Annie O’Neal

Armand Schultz as David Case