Melissa Gilbert as Laura Ingalls Wilder

Dean Butler as Almanzo Wilder

Richard Bull as Nels Oleson

Victor French as Isaiah Edwards

Kevin Hagen as Dr. Hiram Baker

Dabbs Greer as Rev. Robert Alden

Jonathan Gilbert as Willie Oleson

Allison Balson as Nancy Oleson

Stan Ivar as John Carter

Pamela Roylance as Sarah Carter

Lindsay Kennedy as Jeb Carter

David Friedman as Jason Carter

Shannen Doherty as Jenny Wilder

Leslie Landon as Etta Plum

Robert Casper as Sherwood Montague

Sherri Stoner as Rachel Brown Oleson

Cooper Huckabee as Vance Reed

Melora Hardin as Michele Pierson

Henry Brandon as Otis Wagner

James T. Callahan as Doctor Houser

Charles Cyphers as Zack Taylor

Michael Landon as Charles Ingalls

Matthew Labyorteaux as Albert Ingalls

Victor Izay as Thomas Hall

Erik Holland as Gunnar Lindstrom

Shonda Whipple as Amy Bryant

Lois Hall as Secretary

Robert Balderson as Doctor

Jack Lilley as Townsman

Bob Miles as Townsman #2