Jeff Bridges as Father Daniel Flynn / Dock O'Kelly

Cynthia Erivo as Darlene Sweet

Lewis Pullman as Miles Miller

Dakota Johnson as Emily Summerspring

Cailee Spaeny as Rose Summerspring

Jon Hamm as Laramie Seymour Sullivan / Dwight Broadbeck

Chris Hemsworth as Billy Lee

Nick Offerman as Felix O'Kelly

Xavier Dolan as Buddy Sunday

Shea Whigham as Dr. Woodbury Laurence

Mark O'Brien as Larsen Rogers

Charles Halford as Sammy Wilds

Jim O'Heir as Milton Wyrick

Gerry Nairn as Reporter Paul Kraemer

Alvina August as Vesta Shears

London Morrison as Angela Harris, Vesta's Backup Singer

Bethany Brown as Florence Lemons, Vesta's Backup Singer

Rebecca Toolan as Helen Gandy

Hannah Zirke as Young Emily Summerspring

Billy Wickman as Hutch Summerspring

Charlotte Mosby as Young Rose Summerspring

William B. Davis as Judge Gordon Hoffman

Manny Jacinto as Waring 'Wade' Espiritu

Tally Rodin as Silvana 'Millie' Melvin

Sophia Lauchlin Hirt as Annabell Czuchlewski

Jonathan Whitesell as Chris 'Flicker' Grimes

Synto D. Misati as Norris 'Roman' Kindel

Austin A.J. Abell as Young Miles Miller

Katharine Isabelle as Auntie Ruth Pugh

Sarah Smyth as Ginger Miller

Richard Nixon as Self (archive footage)

Jocelyne Gaumond as Keno Girl (uncredited)

Austin James as Soldier (uncredited)

Caroline Koziol as Ivona (uncredited)

James Quach as NVA Captain (uncredited)

John Specogna as District Attorney (uncredited)

Stephen Stanton as J. Edgar Hoover (uncredited)

Vincent Washington as Sergeant Renfro (uncredited)