James Marsden as Warren Strobel

Woody Harrelson as Jonathan Landay

Rob Reiner as John Walcott

Jessica Biel as Lisa Mayr

Milla Jovovich as Vlatka Landay

Tommy Lee Jones as Joe Galloway

Richard Schiff as The Usual

Teri Wyble as Pam

Al Sapienza as Arthur

Wayne Pére as Intelligence Source

Steve Coulter as Looney Tunes

Terence Rosemore as Mr. Green

Margo Moorer as Mrs. Green

Michael Harding as Freud

Kate Butler as Nancy Walcott

Luke White as Adam Strobel

Gabe White as Mitch Strobel

Bowen Hoover as Noah Landay

Caroline Fourmy as Beryl Adcock

Gretchen Koerner as K-10

Jake Reiner as Congressional Staffer

Julie Mun as Administration Official

Marcus Lyle Brown as Intelligence Official

Anthony Reynolds as Middle East Expert

Han Soto as Nuclear Weapons Expert

Jay Seals as Senate Aide

Carl Palmer as Senate Chairman

Michael Harrity as State Department Staffer

Jack Topalian as Ahmed Chalabi

Ned Yousef as Entifadh Qanbar

Stephanie Honoré as Clueless Journalist

Ariadne Joseph as Eager Journalist

J. Omar Castro as Intelligent Entertainment Journalist

Ava Knighten Santana as Young Entertainment Journalist

Michael Scott as Young Journalist

Tadasay Young as Publicist

Devyn A. Tyler as Reporter #1

Preston James Hillier as Reporter #2

Lindsay Ayliffe as Mr. Mayr

John Newberg as Mr. Strobel

Tony Bentley as Paul Smucker

David Moncrief as Bill

Terry Dale Parks as Dixie

Ameer Baraka as Middle-Aged Reporter

Alex Collins as Armed Leader

Josh Ahrens as Army Recruiter

William Curtis Coppersmith as Drill Sergeant #1

Larry McGhee as Drill Sergeant #2

Andrew Najar as Drill Sergeant #3

Michelle Taylor as Dater #1

Heath F. Borne as Dater #2

Shayne Tingle as Dater #3

Christopher Gill as Dater #4

Elisa Gabrielli as Loose Nukes (voice)

Jack Blessing as Man on Phone (voice)

Milena Mortati as Italian Lady (voice)

Osama bin Laden as Self (archive footage)

Aaron Mitchell as Journalist (uncredited)

Joe Lieberman as Self (archive footage)