Alberto Testone as Michelangelo Buonarroti

Umberto Orsini as Marchese Malaspina

Nicola Adobati as Lorenzo de Medici duca d'Urbino

Massimo De Francovich as Papa Giulio II

Nicola De Paola as Cardinale Giulio De' Medici

Glen Blackhall as Raffaello

Orso Maria Guerrini as Marchese Malaspina

Alexandra Deynega as Maria

Yuliya Vysotskaya as Dama con l'ermellino

Carlo Capalbo as Soldier

Adriano Chiaramida as Ludovico Buonarroti

Jakob Diehl as Peppe

Ralph Palka as Peppe (voice)

Glen Blackhall as Raphael

Antonio Gargiulo as Francesco Maria della Rovere

Toni Pandolfo as Dante Alighieri

Federico Vanni as Jacopo Sansovino

Anita Pititto as Marchesa D'Este / Malaspina

Simone Toffanin as Pope Leo X

Francesco Gaudiello as Pietro

Daniele Ferretti as Notary

Riccardo Landi as Al Farab

Alessandro Pezzali as Lionardo Buonarroti

Mauro Pirovano as Notary

Mirco Sassoli as Il topo

Salvatore Pulzella as Buonarroto Buonarroti

Roberto Serpi as Giovan Simone Buonarroti