Isabela Merced as Dora

Jeffrey Wahlberg as Diego

Madeleine Madden as Sammy

Eugenio Derbez as Alejandro Gutierrez

Michael Peña as Cole - Dora's Father

Eva Longoria as Elena

Benicio del Toro as Swiper (voice)

Madelyn Miranda as Dora (6 years)

Malachi Barton as Diego (6 years)

Dee Bradley Baker as Animal Vocalizations (voice)

Sasha Toro as Backpack (voice)

Marc Weiner as Map (voice)

Joey Vieira as Nico

Pia Miller as Sabrina - Diego's Mother

Adriana Barraza as Abuela Valerie

Damien Garvey as Security Guard

Anikka Abelita as Vegan Student

Daniel Donaldson as Bad Dancing Teacher

Nicholas Coombe as Randy

Tivon Toito'ona as Soccer Team Kid 1

Emily Bell as Soccer Team Kid 4

Jace Fleming as Mean Kid

Michelle Collins as English Teacher

Bailey Hendy as Soccer Team Kid 2

Darcy Worthington as Soccer Team Kid 3

Matthew Okine as Teacher

Natasa Ristic as Christina X

Christopher Kirby as Viper

Temuera Morrison as Powell

Christopher Rawlins as Mercenary

Isela Vega as Old Woman

Danny Trejo as Boots (voice)

Q'orianka Kilcher as Kawillaka

Natalie Kinghorn as High School DJ

Daniel Valle as High School Dancer / Assistant Choreographer

Kate Wormald as High School Dancer / Assistant Choreographer

Abdulaye Sow as High School Dancer

Brooke Schembri as High School Dancer

Dustin Taylor as High School Dancer

Elke Tulip Paes as High School Dancer

Georgia Rothera as High School Dancer

James David Portas as High School Dancer

Joel Murphy as High School Dancer

Kalahni Mia Spink as High School Dancer

Karin Mochizuki as High School Dancer

Kristin Sparks as High School Dancer

Leyton Oliver Bartley Beal as High School Dancer

Ly Thanh Dat as High School Dancer

Mitchell Adam Marshman as High School Dancer

Phoenix Mitchell as High School Dancer

Sarah Louise Harvey as High School Dancer

Savannah La Rain as High School Dancer

Seraseini Momo as High School Dancer

Tanisha Pili Mvoyi as High School Dancer

William James Dyson as High School Dancer

Zeke Azzolini as High School Dancer

Emilia Lau as Crowd High School Student

Caleb McLaughlin as Tico (voice)

Braden Lewis as Airport Kid

Vanesa Everett as Mixed Nationality Tourist (uncredited)