James Stewart as John Michael ('Chip') Hardesty

Vera Miles as Lucy Ann Hardesty

Murray Hamilton as Sam Crandall

Larry Pennell as George Crandall

Nick Adams as John Gilbert ('Jack') Graham

Diane Jergens as Jennie Hardesty

Jean Willes as Anna Sage

Joyce Taylor as Anne Hardesty

Victor Millan as Mario

Parley Baer as Harry Dakins

Paul Genge as "Whitey"

Fay Roope as Dwight McCutcheon

Ed Prentiss as U.S. Marshal

Robert Gist as Medicine Salesman

Buzz Martin as Mike Hardesty

Ken Mayer as Casket Salesman (as Kenneth Mayer)

Michael Smith as George Crandall at 12 (uncredited)

Patrick Whyte as Major (uncredited)

Al McGranary as Mr. Ballard (uncredited)

Victor Adamson as Train Passenger (uncredited)

Luana Anders as Mrs. Graham (uncredited)

Audley Anderson as Farmer (uncredited)

Herb Armstrong as Frank Nash (uncredited)

Eleanor Audley as Mrs. King - Graham's Mother (uncredited)

Benjie Bancroft as FBI Agent (uncredited)

David Barclay as FBI Agent #3 (uncredited)

Fern Barry as Farmer's Wife (uncredited)

Charles Bateman as FBI Agent (uncredited)

Barbara Beall as Party Guest (uncredited)

Kimberly Beck as Jennie Hardesty at 2 (uncredited)

Shirley Bonne as Party Guest (uncredited)

Nesdon Booth as Sandy - Driver (uncredited)

Richard Boyer as Ticket Agent (uncredited)

Chet Brandenburg as Construction Worker (uncredited)

Jerry Brent as Western Union Boy (uncredited)

Lowell Brown as Party Guest (uncredited)

Peter Brown as FBI Agent at Hearting (voice) (uncredited)

Charles Brunner as Bill Smith (uncredited)

Theona Bryant as Edith Crandall (uncredited)

Henry Casso as Man in Phone Booth (uncredited)

Dick Cherney as FBI Agent (uncredited)

Robert Clarke as Bartender (uncredited)

Mary Lou Clifford as Indian Switchboard Operator (uncredited)

Bud Cokes as FBI Agent (uncredited)

Alan Craig as Fred Barker (uncredited)

Jane Crowley as Ma Barker (uncredited)

John Damler as Denver S.A.C. (uncredited)

Jeanne Dante as Party Guest (uncredited)

Susan Davis as Party Guest (uncredited)

Angelo De Meo as Fred Hunter (uncredited)

Sayre Dearing as Airport Employee (uncredited)

Gabriel Del Valle as Argentine Policeman (uncredited)

Vera Denham as Farmer's Wife (uncredited)

Paul Denton as FBI Agent (uncredited)

Ann Doran as Mrs. Ballard (uncredited)

Joan Dupuis as Party Guest (uncredited)

Robin Eccles as Anne Hardesty at 4 (uncredited)

Mary Ann Edwards as Marge (uncredited)

Tippy Elam as Shoeshine Boy (uncredited)

Ben Erway as Justice Dept. Lawyer (uncredited)

Ella Ethridge as Farmer's Wife (uncredited)

Sam Flint as Doctor (uncredited)

George Ford as Plane Passenger (uncredited)

Terry Frost as Craig (uncredited)

Michael Garrett as Insurance Salesman (uncredited)

Kenneth Gibson as Graduation Audience Member (uncredited)

Arthur D. Gilmour as Major (uncredited)

James Gonzalez as FBI Agent (uncredited)

Roy Gordon as Emmett Reese (uncredited)

Rand Harper as Assistant Denver S.A.C. (uncredited)

Elizabeth Harrower as Clerk (uncredited)

Harry Harvey as Mrs. King's Neighbor (uncredited)

Les Hellman as Kirby (uncredited)

Jack Henderson as Hardware Store Owner (uncredited)

Tex Holden as Townsman (uncredited)

Judd Holdren as Party Guest (uncredited)

J. Edgar Hoover as J. Edgar Hoover (uncredited)

Rand Hopper as Assistant Denver S.A.C. (uncredited)

Carroll House as Dover (uncredited)

Sid Kane as George Metzger - Espionage Agent (uncredited)

Stacy Keach, Sr. as Machine Gun Kelly (uncredited)

Rickey Kelman as Mike Hardesty at 10 (uncredited)

George Khoury as Alvin Karpis (uncredited)

Walter Kightly as FBI Agent (uncredited)

Kay E. Kuter as Barber (uncredited)

Morgan Lane as Party Guest (uncredited)

Eddie Little Sky as Henry Roanhorse (uncredited)

Robert Locke Lorraine as Plane Passenger (uncredited)

William Lovett as Party Guest (uncredited)

Jenni Lynn as Jennie Hardesty at 4 (uncredited)

Ted Mapes as FBI Agent (uncredited)

Lori Martin as Anne Hardesty at 8 (uncredited)

Russ McCubbin as Ku Klux Klan Member / Man Setting In Diner (uncredited)

David McMahon as Klansman (uncredited)

Tom Monroe as Klansman (uncredited)

Ray Montgomery as Driver (uncredited)

Burt Mustin as Uncle Fudd Schneider (uncredited)

Dorothy Neumann as Landlady (uncredited)

Ron Nyman as Commuter at Airport (uncredited)

Alan Paige as Checker (uncredited)

George Pembroke as Chief of Civil Aeronautics Board (uncredited)

Bob Peoples as Sam Cowley (uncredited)

Scott Peters as John Dillinger (uncredited)

Bob Peterson as Pretty Boy Foyd (uncredited)

William Phipps as Baby Face Nelson (uncredited)

John Pickard as Klansman (uncredited)

Murray Pollack as FBI Agent (uncredited)

Jim Porcupine as Indian Switchboard Operator (uncredited)

James Porta as Argentine Policeman (uncredited)

Charles Postal as Justice Dept. Lawyer (uncredited)

John Quijada as Argentine Policeman (uncredited)

Paul Ravel as Counterman (uncredited)

Grandon Rhodes as Minister at Funeral (uncredited)

Herman Rudin as Hoodlum (uncredited)

Emily All Runner as Servant Girl (uncredited)

Grant Scott as Party Guest (uncredited)

George Selk as Organist / Janitor (uncredited)

Dorothy Skyeagle as Rita Smith (uncredited)

Mabel Smaney as Passerby Outside Theatre (uncredited)

Gil Smith as Mike Hardesty at 6 (uncredited)

Paul Smith as Albert Shaw (uncredited)

Charles Soldani as Indian on Train (uncredited)

Bert Spencer as FBI Agent (uncredited)

Vincent St. Cyr as Dan Savagehorse (uncredited)

Glenn Stensel as Undetermined Secondary Role (uncredited)

Michael Switlick as Anne's 3-Year-Old Son (uncredited)

Forrest Taylor as Wedding Minister (uncredited)

Guy Teague as Deputy Marshal (uncredited)

Jack Tesler as Operator (uncredited)

Roy Thinnes as Party Guest (uncredited)

William J. Thomas as Janitor (uncredited)

Clyde Tolson as FBI Agent (uncredited)

Alfred Tonkel as Druggist (uncredited)

John Truax as Boyd (uncredited)

John Varnum as Brackenridge (uncredited)

James Vickery as Schaeffer (uncredited)

Elmore Vincent as Farmer (uncredited)

Ed Wagner as Sawyer (uncredited)

Selene Walters as Polly (uncredited)

Maurice Wells as Speaker (uncredited)

Adam West as Man on Two-Way Radio (voice) (uncredited)

Will J. White as Silvano / J. Edgar Hoover (uncredited)

Guy Wilkerson as Cliff Eberhardt (uncredited)

Tom Wilson as Chicago Passerby (uncredited)

Herbert Winters as FBI Agent (uncredited)

Britt Wood as Farmer (uncredited)

Roque Ybarra as Murdered Indian (uncredited)

Chief Yowlachie as Harry Willowtree (uncredited)