John Larroquette as Mark Bannister

Kirstie Alley as Jessie Bannister

John Diehl as Fred

Alison La Placa as Claudia

Jessica Lundy as Bernice

Bradley Gregg as Jonathan

Dennis Miller as Wes

Robert Ginty as Dale

Wayne Tippit as Grindle

Paul Eiding as Stark

Aeryk Egan as C.K.

Deborah Otto as Katy

Mark Bringelson as Prick Automaton Cop

Karen Kronwell as Female Cop

Heather McNair as Karen Kelly

Mark Manning as Russell Fenn

Bob Sorenson as Field Reporter

Rob Camilletti as Shady Character Outside Strip Joint

Elizabeth Lang as Mark's Secretary

Peppi Sanders as Receptionist

Jay Bernard as Kaminsky

Frank Dworsky as Mailroom Employee

Rene L. Moreno as Mailroom Runner

Deborah Swartz as Chloroform

Lisa Rubin as Tom Cruise Girl Fan

Hart Throb as Tom Cruise Guy Fan

Aaron Berger as Space People Eat My Mom And Dad

Elaine Moe as Fistful of Valium

Loy Burns as Get Drunk

Jack Edward as Polka Man

Pat Willoughby as Polka Lady

Richard Alexander as Bust Somebody

Francis Brooks as Pump Iron

Marlon Darton as Meditation

Frieda Smith as Sex

Jon Proudstar as Shoot 'Em

Mel Coleman as Strangle 'Em

Kimberly Steuter as Cook 'Em in the Owen

Elizabeth Kneeland as Hide His Medication

Ed Peterson as Her Ancient Husband

Grant Moran as Kindness

Michael Waltman as Insulin

Darwin Hall as Hammer

Karen DeConcini as Bean Dip

Earl Smith as Shiv

Kevin Wadowski as Hit 'N' Run

Ethan Aronson as His Car

Michael Zand as Kaddir (voice)

Jack Penix as Dr. Jack Penix O.B. Gyn (voice)

Jonny Bliss as Employee

Rich Hopkins as Tourist

Michael Listorti as Tv news cameraman

Earl W. Smith as Street Thug