Marg Helgenberger as Hannah Montgomery

Betty Gilpin as Gloria Mitchell

Henry Lau as Trent

Kathryn Prescott as Clarity June "CJ" Mitchell

Dennis Quaid as Ethan Montgomery

Josh Gad as Bailey / Molly / Big Dog / Max (voice)

Abby Ryder Fortson as Young CJ

Emma Volk as Toddler CJ

Ian Chen as Young Trent

Jake Manley as Shane

Johnny Galecki as Henry Montgomery

Tyler Asher Xin-Qin as Saint

Beckett Richard Pin as 15-Month-Old Saint

Daniela Barbosa as Liesl

Kevin Claydon as Barry

Arlene Duncan as Hilda

Cherissa Richards as Joan

Kenneth Liu as Trent's Dad

Stefanie Wiens as

Angela Narth as Old Woman

Sally Shepard as Tour Bus Ticket Taker (uncredited)

Conrad Coates as Big Joe