Brady Noon as Greg Heffley (voice)

Ethan William Childress as Rowley Jefferson (voice)

Hunter Dillon as Rodrick Heffley (voice)

Erica Cerra as Susan Heffley (voice)

Chris Diamantopoulos as Frank Heffley (voice)

Ed Asner as Grandpa Heffley (voice)

Linda Lavin as Barb (voice)

Loretta Devine as Irene (voice)

Priscilla Lopez as Merle (voice)

Nathan Arenas as Mackie (voice)

Albert Tsai as Drew (voice)

Hudson Yang as Larry (voice)

Jimmy Tatro as Bill (voice)

Kimberly Brooks as News Anchor (voice)

Gracen Newton as Manny (voice)

Vincent Tong as Leland (voice)

Veena Sood as Elevator Lady (voice)

Ava Acres as Additional Voices (voice)

Sky Alexis as Additional Voices (voice)

Noah Kaye Bentley as Additional Voices (voice)

Asher Bishop as Additional Voices (voice)

Jen Cain as Additional Voices (voice)

Tristan Allerick Chen as Additional Voices (voice)

Juliet Donenfeld as Additional Voices (voice)

Marley Garner as Additional Voices (voice)

Johnny Gidcomb as Additional Voices (voice)

Lex Lang as Additional Voices (voice)

Michael Leone as Additional Voices (voice)

Ava Mae Leslie as Additional Voices (voice)

Susan Leslie as Additional Voices (voice)

Matt Nolan as Additional Voices (voice)

Andre Robinson as Additional Voices (voice)

Benjamin Valic as Additional Voices (voice)

Paul-Mikél Williams as Additional Voices (voice)

ViviAnn Yee as Additional Voices (voice)

Ruth Zalduondo as Additional Voices (voice)