Meryl Streep as Kate Gulden

Renée Zellweger as Ellen Gulden

William Hurt as George Gulden

Tom Everett Scott as Brian Gulden

Lauren Graham as Jules

Nicky Katt as Jordan Belzer

James Eckhouse as District Attorney

Patrick Breen as G.A. Tweedy

Gerrit Graham as Oliver Most

David Byron as Senator Sullivan

Stephen Peabody as Harold

Lizbeth MacKay as Dr. Cohen

Mary Catherine Wright as Clarice

Sloane Shelton as Evelyn Best

Michele Shay as June

Bobo Lewis as Muriel

Marylouise Burke as Louisa

Marcia Jean Kurtz as Marcia

Diana Canova as Diana

John Deyle as Santa / Mayor

Hallee Hirsh as Ellen - Age 8

Jeffrey Scaperrotta as Brian - Age 4

Todd Cerveris as Casey

Anna Carolina Alvim as Nurse Teresa

Julie Janney as Hospital Nurse

Susan Stout as Tweedy's Secretary

Greg Hedtke as Magazine Executive

Christian James as Magazine Executive

Lauren Toub as Halloween Girl

Ashley Remy as Halloween Girl

Saul Williams as Graduate Student

Julianne Nicholson as College Student

Amber Kain as College Student

Yolande Bavan as Nari

Benjamin Andrews as Party Kid

Kathryn Walsh as Party Kid