Anne Hathaway as Grand High Witch

Octavia Spencer as Grandma

Stanley Tucci as Mr Stringer

Jahzir Bruno as Hero Boy

Chris Rock as Older Hero (voice)

Codie-Lei Eastick as Bruno Jenkins

Kristin Chenoweth as Daisy / Mary (voice)

Charles Edwards as Mr Jenkins

Morgana Robinson as Mrs Jenkins

Brian Bovell as Reginald

Josette Simon as Zelda

Eugenia Caruso as Consuella

Ana Maria Maskell as Esmerelda

Amber Flanagan as Esmeralda

Eurydice El-Etr as Samantha

Orla O'Rourke as Saoirse

Penny Lisle as Lana

Dempsey Bovell as Jesup

Jonathan Livingstone as Raymond

Paul Leonard as Maitre'D - Luther

Simon Manyonda as Sous Chef

Philippe Spall as Chef

Abi Adeyemi as Witch

Anastasia Zabarchuk as Witch

Katie Hardwick as Witch

Vivienne Acheampong as Alice's Mum

Sobowale Antonio Bamgbose as Alice's Dad

Lunga Skosana as Grandma's Mother

Miranda Sarfo Peprah as Young Grandma

Joseph Zinyemba as Basketball Kid

Me'sha Bryan as Chambermaid

Cyril Nri as Chief Doorman

Joshua Neil as Officer Perry

Ken Nwosu as Bellman

Angus Wright as Waiter

Sarah T. Cohen as Witch

Rachel Sophia-Anthony as Shop Customer (uncredited)