Tim Blake Nelson as Buster Scruggs (segment "The Ballad of Buster Scruggs")

Willie Watson as The Kid (segment "The Ballad of Buster Scruggs")

Clancy Brown as Curly Joe (segment "The Ballad of Buster Scruggs")

Danny McCarthy as Curly Joe's Brother (segment "The Ballad of Buster Scruggs")

David Krumholtz as Frenchman (segment "The Ballad of Buster Scruggs")

Thomas Wingate as Gun Check Man (segment "The Ballad of Buster Scruggs")

Tim DeZarn as Mean-Eyed Card Player (segment "The Ballad of Buster Scruggs")

E.E. Bell as Piano Player (segment "The Ballad of Buster Scruggs")

Alejandro Patiño as Cantina Bartender (segment "The Ballad of Buster Scruggs")

Tom Proctor as Cantina Bad Man (segment "The Ballad of Buster Scruggs")

Clinton Roberts as Cantina Scum (segment "The Ballad of Buster Scruggs")

Matthew Willig as Cantina Scum (segment "The Ballad of Buster Scruggs")

Jesse Youngblood as Cantina Scum (segment "The Ballad of Buster Scruggs")

J.J. Dashnaw as Cantina Scum (segment "The Ballad of Buster Scruggs")

James Franco as Cowboy (segment "Near Algodones")

Stephen Root as Teller (segment "Near Algodones")

Ralph Ineson as Posse Leader (segment "Near Algodones")

Mike Watson as Posse (segment "Near Algodones")

Brian Brown as Posse (segment "Near Algodones")

Ryan Brown as Posse (segment "Near Algodones")

Richard Bucher as Posse (segment "Near Algodones")

Jesse Luken as Drover (segment "Near Algodones")

Michael Cullen as Judge (segment "Near Algodones")

Austin Rising as Bailiff (segment "Near Algodones")

James 'Scotty' Augare as Comanche Chief (segment "Near Algodones")

Liam Neeson as Impresario (segment "Meal Ticket")

Harry Melling as Artist (segment "Meal Ticket")

Jiji Hise as The Bawd (segment "Meal Ticket")

Paul Rae as Chicken Impresario (segment "Meal Ticket")

Tom Waits as Prospector (segment "All Gold Canyon")

Sam Dillon as Young Man (segment "All Gold Canyon")

Bill Heck as Billy Knapp (segment "The Gal Who Got Rattled")

Zoe Kazan as Alice Longabaugh (segment "The Gal Who Got Rattled")

Grainger Hines as Mr. Arthur (segment "The Gal Who Got Rattled")

Jefferson Mays as Gilbert Longabaugh (segment "The Gal Who Got Rattled")

Prudence Wright Holmes as Boarding House Landlady (segment "The Gal Who Got Rattled")

Eric Petersen as Boarder (segment "The Gal Who Got Rattled")

Doris Hargrave as Boarder (segment "The Gal Who Got Rattled")

Jackamoe Buzzell as Boarder (segment "The Gal Who Got Rattled")

Ethan Dubin as Matt (segment "The Gal Who Got Rattled")

Jordy Laucomer as Whipped Boy (segment "The Gal Who Got Rattled")

Thea Lux as His Mother (segment "The Gal Who Got Rattled")

Bret Hughson as His Father (segment "The Gal Who Got Rattled")

Rod Rondeaux as Sioux Chief (segment "The Gal Who Got Rattled")

Raymond Kurshals as Puppet Dancer (segment "The Gal Who Got Rattled")

Jonjo O'Neill as Englishman (segment "The Mortal Remains")

Brendan Gleeson as Irishman (segment "The Mortal Remains")

Saul Rubinek as Frenchman (segment "The Mortal Remains")

Tyne Daly as Lady (segment "The Mortal Remains")

Chelcie Ross as Trapper (segment "The Mortal Remains")

Martin Palmer as Blubberer (segment "Near Algodones") (uncredited)

Billy Lockwood as Father (segment "The Gal Who Got Rattled") (uncredited)

Stephen R. Estler as Gambler (segment "The Ballad of Buster Scruggs") (uncredited)

Grace LeSueur as Pretty Girl at Gallows (segment "Near Algodones") (uncredited)

Bill Foster as Saloon Man (segment "The Ballad of Buster Scruggs") (uncredited)