Harrison Ford as Richard Kimble

Tommy Lee Jones as Samuel Gerard

Joe Pantoliano as Cosmo Renfro

Jeroen Krabbé as Charles Nichols

Daniel Roebuck as Biggs

L. Scott Caldwell as Poole

Tom Wood as Newman

Ron Dean as Detective Kelly

Joseph F. Kosala as Detective Rosetti

Andreas Katsulas as Frederick Sykes

Sela Ward as Helen Kimble

Julianne Moore as Anne Eastman

Miguel Nino as Chicago Cop #1

John Drummond as Newscaster

Tony Fosco as Chicago Cop #2

Joseph F. Fisher as Otto Sloan

James Liautaud as Paul

David Darlow as Dr. Lentz

Tom Galouzis as Surgeon

James F. McKinsey as Surgeon

Mark D. Espinoza as Resident

John E. Ellis as Anesthesiologist

Gene Barge as 11th District Cop

Thomas Charles Simmons as 11th District Cop

Joe Guzaldo as Prosecutor

Dick Cusack as Walter Gutherie

Nicholas Kusenko as Assistant Defense Attorney

Joan Kohn as Assistant Prosecuting Attorney

Joe Guastaferro as Coroner

Andy Romano as Judge Bennett

Richard Riehle as Old Guard

Thom Vernon as Carlson

Ken Moreno as Partida

Eddie Bo Smith Jr. as Copeland

Frank Ray Perilli as Jail Officer

Otis Wilson as Jail Officer

Pancho Demmings as Young Guard

Jim Wilkey as Bus Driver

Danny Goldring as Head Illinois State Trooper

Nick Searcy as Sheriff Rawlins

Kevin Crowley as State Trooper

Michael James as Head Welder

Michael Skewes as Highway Patrolman

Ila Cathleen Stallings as Duty Nurse

Linda Casaletto as Rural Hospital Nurse

Cody Glenn as Paramedic

Cynthia Baker as Woman in Car

Johnny Lee Davenport as Marshal Henry

Mike Bacarella as Marshal Stevens

Bill Cusack as Tracing Technician

David U. Hodges as Marshal David

Lillie Richardson as Copeland's Girlfriend

Peter J. Caria IV as Billy

Tighe Barry as Windshield Washer

Monika Chabrowski as Polish Landlady

Lonnie Sima as Landlady's Son

Oksana Fedunyszyn as Myoelectric Receptionist

Orlando García as Desmondo

Afram Bill Williams as Salesman

Bruce L. Gewertz as Dr. Bruce

Jane Lynch as Kathy Wahlund

Joseph Rotkvich as Officer Joseph

Steven Lilovich as Officer Steve

Noelle Bou-Sliman as Myoelectric Technician

Roxanne Roberts as Trauma Doctor

Alex P. Hernandez as Trauma Doctor

Theron Touché Lykes as Orderly

Joel Robinson as Boy Patient

Greg Hollimon as Skating Orderly

Cheryl Lynn Bruce as O.R. Doctor

Marie Ware as Nurse Gladys

Bernard McGee as Man

Ann Whitney as Myoelectric Director

Lily Monkus as Desk Clerk

Willie Lucas as Desk Clerk

Turk Muller as Clearing Officer

Ana María Alvarez as La Cubana

Eugene F. Crededio as Visitation Guard

Maurice Person as Clive Driscoll

Terry Hard as Officer Hormel

Pam Zekman as Newscaster

David Pasquesi as Newscaster

Brent Shaphren as Doctor at Bar

Stephen A. Landsman as Doctor at Bar

B.J. Jones as Doctor at Bar

Dru Anne Carlson as Gerard's Secretary

Margaret Moore as Nichols' Assistant

Manny Lopez as Seminar Doctor

John M. Watson Sr. as Bones Roosevelt

Kirsten Nelson as Betty

Juan Ramírez as Man on 'El'

Neil Flynn as Transit Cop

Allen Hamilton as Host

Eric Fudala as Hotel Security Guard

Lester Holt as Newscaster

Jay Levine as Newscaster

Sal Richards as Warrant Captain (uncredited)

Darren W. Conrad as Deputy at Train Wreck (uncredited)

Kevin Mukherji as Doctor (uncredited)

John-Clay Scott as Mad Motorist at Tunnel (uncredited)

Suzy Brack as City Hall Employee (uncredited)

Gene Kelly as US Marshall (uncredited)