Paul Mescal as Lucius

Denzel Washington as Macrinus

Pedro Pascal as General Acacius

Connie Nielsen as Lucilla

Joseph Quinn as Emperor Geta

Fred Hechinger as Emperor Caracalla

Lior Raz as Viggo

Derek Jacobi as Gracchus

Peter Mensah as Jugurtha

Matt Lucas as Master of Ceremonies

Alexander Karim as Ravi

Yuval Gonen as Arishat

Richard McCabe as Quaestor

Tim McInnerny as Senator Thraex

Alec Utgoff as Darius

Rory McCann as General Tegula

Yann Gael as Bostar

Riana Duce as Hyacinthia

Alfie Tempest as Young Lucius

Amira Ghazalla as Leta | Lucilla's Servant

Abdelmoula Ait Sidi Lhassan as Boy (Numidia)

Mouaiz El Outmany as Boy (Numidia)

Brahim Assagour as Boy (Numidia)

Alexander Simkin as Centurion (Branding)

Richard Katz as Governor (Baboon Arena)

David Ganly as Master of Ceremonies (Baboon Arena)

Anton Saliba as Praetorian (Lucilla's)

Amal Ayouch as Noble Bedouin Woman

Hadrian Howard as Agedilios

Chidi Ajufo as Gladiator

Lee Charles as Slovak

Christopher Edward Hallaways as Glyceo

Chi Lewis-Parry as Phoebus

Ángel Gómez De La Torre as Gnaeus

Brahim Ait Ben Azzouz as Centurion (Lucius' Arrest)

Maxime Rauf Ruijselaar as Centurion (Ostia)

Sana El Baghdady as Wailing Woman

Nadia El Masnaoui as Wailing Woman

Nisrine Machat as Wailing Woman

Maud Oulhen as Female Concubine

Estelle Courret as Female Concubine

Line Ancel as Female Concubine

Sixtine Gignoux as Female Concubine

Igor Badnjar as Male Concubine

Romi Debart as Male Concubine

Arnaud Préchac as Male Concubine

Tom Moutchi as Brennos

Dean Fagan as Dorso

May Calamawy as Macrinus' Companion (uncredited)