Jake Gyllenhaal as Joe Baylor

Ethan Hawke as Sgt. Bill Miller (voice)

Riley Keough as Emily Lighton (voice)

Peter Sarsgaard as Henry Fisher (voice)

Christina Vidal as Sgt. Denise Wade

Paul Dano as Matthew Fontenot (voice)

Eli Goree as Rick (voice)

Da'Vine Joy Randolph as CHP Dispatcher (voice)

David Castañeda as Tim Gerachi

Adrian Martinez as Manny

Christiana Montoya as Abby (voice)

Gillian Zinser as Jess Baylor (voice)

Aileen Burdock as LA Times Operator (voice)

Bill Burr as Nightclub Caller (voice)

Beau Knapp as Dru Nashe (voice)

Edi Patterson as Katherine Harbor (voice)

Marlene Forte as House on Fire Caller (voice)

Maurice Webster as Gary

Bret Eric Porter as Marion

Sal Lucio as CHP Officer

Becky Wu as Riva

Terence J. Rotolo as CHP Patrolman Rodriguez (voice)

Dillon Lane as Crashed Cyclist (voice)

Oscar Balderrama as Scott

Jaime FitzSimons as Rodriguez's Partner (voice)

Jonathan Hunt as 911 Operator (voice)