Robert De Niro as Det. Mitch Preston

Eddie Murphy as Officer Trey Sellars

Rene Russo as Chase Renzi

William Shatner as William Shatner

Nestor Serrano as Ray

Joy Bryant as Lexi

Yasiin Bey as Lazy Boy

Rachael Harris as Lehrerin

Peter Jacobson as Brad Slocum

Drena De Niro as Annie

Frankie Faison as Lt. Winship

T.J. Cross as ReRun

Judah Friedlander as Julio

James Roday Rodriguez as 'Maxis' Cameraman

Alex Borstein as Casting Director

Kadeem Hardison as Kyle

Pedro Damián as Ceasar Vargas

Johnnie Cochran as Himself

Merlin Santana as Hector

Zaid Farid as Polizeichef Ben

Holly Mandel as Producer

Joel Hurt Jones as Reporter #1

Chris Harrison as Reporter #2

Perri Peltz as Reporter #3

Amy Powell as Reporter #4

Debra Snell as Reporter #5

Chris Ufland as Reporter #6

Andrew Wilson as Locker Room Cop #1

Larry Joe Campbell as Locker Room Cop #2

Reggie Gaskins as Locker Room Cop #3

Ken Hudson Campbell as Cop in Gym

Johnnie L. Cochran Jr. as Johnnie Cochran, ReRun's Lawyer

Rick Cramer as Duty Officer

Linda Hart as Waitress

Maurice Compte as Chili

Freez Luv as Freez

Jullian Dulce Vida as J.J.

Jeff Sanders as Big Boy

Robert Joseph as Gangbanger #4

Angela Alvarado as Gina Reyes

John Cariani as Charlie Hertz

Kirk Ward as Parking Garage Cop #1

Reggie Jordan as Parking Garage Cop #2

Lucille M. Oliver as Screaming Woman

Callie Childers as Pool Girl

Tom Billett as Freddy, Bouncer #2

Henry Kingi as Garbage Truck Driver

Neil Mather as Uniform

Joel Elliott as Animal Welfare Worker #1

Grant Sawyer as Animal Welfare Worker #2

Christopher Darga as Gun Show Announcer

Clement Blake as Gun Show Patron

Lisa Renee Pitts as Female Cop #1

Teresa DePriest as Female Cop #2

John Polce as Police Officer

Greg Bronson as Detective (uncredited)

Heather Charles as Model (uncredited)

Lisa Danielle as (uncredited)

Jackie Di Crystal as Salsa Dancer (uncredited)

Sonya Khazaal as Salsa Dancer (uncredited)

Pui Fan Lee as Mrs. Maggie Snow (uncredited)

Erica Taylor as Nightclub Patron (uncredited)

Marshall Manesh as Convenience Store Owner