Amanda Peet as Sarah Phoenix

Dermot Mulroney as Henry Griffin

Sarah Paulson as Peri

Blair Brown as Eve

Alison Elliott as Terry

Lois Smith as Dr. Imberman

Jonah Meyerson as Kirk

Max Morris as Andrew

Simon Jones as Professor

Jesse Tyler Ferguson as Student

Susan Pourfar as Waitress

Omar Scroggins as Movie Usher

Adam Kulbersh as Stu Knoepflemacher

Adriane Lenox as Doctor

Novella Nelson as Maya Restaurant Owner

Brian Klugman as Beach Stud

Sile Bermingham as Lilly

Steven Randazzo as Cop #1

Ted Koch as Cop #2

Dana Eskelson as Mother with Stroller

Jonathan Dokuchitz as Man on Street

Michael Showalter as Terry's Fiancé

Fred Armisen as

John Farrer as Hospital Doctor (uncredited)

Chuck Gerena as Water Tower Painter (uncredited)

Robert Oppel as Tattooed Student (uncredited)

Kristen Silverman as Bikini Babe (uncredited)