Kyla Pratt as Penny Proud (voice)

Tommy Davidson as Oscar Proud (voice)

Paula Jai Parker as Trudy Parker-Proud (voice)

Jo Marie Payton as Suga Mama (voice)

Orlando Brown as Sticky Webb (voice)

Soleil Moon Frye as Zoey (voice)

Alisa Reyes as LaCienega Boulevardez (voice)

Karen Malina White as Dijonay Jones (voice)

Omarion as Fifteen Cent (voice)

Arsenio Hall as Dr. Carver / Bobby Proud (voice)

Tara Strong as Bebe Proud / Cece Proud / Cashew (voice)

Jeremy Suarez as Wally (voice)

Carlos Alazraqui as Puff / Board Member (voice)

Alvaro Guttierez as Papi (voice)

Phil LaMarr as Dr. Carver in Disguise / Board Member (voice)

Aries Spears as Wizard Kelly / Board Member (voice)

Raquel Lee as Nubia (voice)

Carlos Mencia as Felix (voice)

Maria Canals-Barrera as Sunset / Newscaster Peanut (voice)

Big Boy as Self (voice)

Keith David as Bebe Clone (voice)

Patricia Belcher as Miss Hightower (voice)

Michele Lisette Jennings as Board Member / T.V. Show Peanut (voice)

LisaRaye McCoy as Choreographer (voice)

Billy West as Board Member / Cab Driver (voice)

Christian Mills as Attorney / Hot Dog Vendor (voice)

Kevin Michael Richardson as Sea Beast / The Mangler / Narrator (voice)

Masi Oka as Japanese Kid / Announcer (voice)