Joaquim de Almeida as Sherlock Holmes

Anthony O'Donnell as Dr Watson

Letícia Sabatella as Esperidiana

Cláudia Abreu as Baroness Maria Luiza

Cláudio Marzo as Dom Pedro II

Maria de Medeiros as Sarah Bernhardt

Marco Nanini as Mello Pimenta

Thalma de Freitas as Ana Candelária

Caco Ciocler as Miguel Lara

Marcello Antony as Marquês de Sales

Maurício Gonçalves as José do Patrocínio

Malu Galli as Chiquinha Gonzaga

Marcello Escorel as Olavo Bilac

Antônio Pompêo as Mukumbe

Emiliano Queiroz as Dr. Saraiva

Agildo Ribeiro as Delegado

Jô Soares as Desembargador

Ary França as Haroldo

Clementino Kelé as Pai-de-santo

Joana Almeida as

Manuela Paulo as Dançarina

Maria Ribeiro as Glória

Otávio Müller as Nina Millet