George Clooney as Matt King

Shailene Woodley as Alexandra King

Amara Miller as Scottie King

Nick Krause as Sid

Patricia Hastie as Elizabeth King

Grace A. Cruz as Scottie's Teacher

Kim Gennaula as School Counselor

Karen Kuioka Hironaga as Barb Higgins

Carmen Kaichi as Lani Higgins

Kaui Hart Hemmings as Matt's Secretary Noe

Beau Bridges as Cousin Hugh

Matt Corboy as Cousin Ralph

Matt Esecson as Cousin Hal

Michael Ontkean as Cousin Milo

Stanton Johnston as Cousin Stan

Jon McManus as Cousin Six

Hugh Foster as Cousin Wink

Tiare R. Finney as Cousin Connie

Tom McTigue as Cousin Dave

Milt Kogan as Dr. Johnston

Mary Birdsong as Kai Mitchell

Rob Huebel as Mark Mitchell

Laird Hamilton as Troy Cook

Aileen "Boo" Arnold as Dorm Supervisor

Esther Kang as Alex's Roommate

Melissa Kim as Alex's Drunken Friend

Robert Forster as Scott Thorson

Barbara L. Southern as Alice "Tutu" Thorson

Celia Kenney as Reina

Matt Reese as Buzz

Zoel Turnbull as Hotel Clerk

Matthew Lillard as Brian Speer

Judy Greer as Julie Speer

Linda Rose Herman as Grief Counselor

Scott Michael Morgan as Barry Thorson

Darryl K. Gonzales as Tahiti Nui Singer (Kanak Attack)

Koko Kanealii as Tahiti Nui Singer (Kanak Attack)

Romey "Keola" Yokotake as Tahiti Nui Singer (Kanak Attack)

Fileena Bahris as Passenger (uncredited)

Dennis Falt as Airplane Passenger (uncredited)

Sisa Grey as Nurse (uncredited)

Tom Holowach as Cousin (uncredited)

Dane Justman as Drunk Guy (uncredited)

James Koons as Attorney (uncredited)

John A. Weaver as Cousin (uncredited)

Larry Wegger as Airline Passenger (uncredited)

Joseph Wilson as Cousin (uncredited)

Joji Yoshida as Troy's Friend (uncredited)