Dustin Hoffman as Sam Daniels

Rene Russo as Robby Keough

Morgan Freeman as General Billy Ford

Kevin Spacey as Casey Schuler

Cuba Gooding Jr. as Major Salt

Donald Sutherland as General Donald McClintock

Patrick Dempsey as Jimbo Scott

Zakes Mokae as Dr. Benjamin Iwabi

Malick Bowens as Dr. Raswani

Susan Lee Hoffman as Dr. Lisa Aronson

Benito Martinez as Dr. Julio Ruiz

Bruce Jarchow as Dr. Mascelli

Leland Hayward III as Henry Seward

Daniel Chodos as Rudy Alvarez

Dale Dye as Colonel Briggs

Kara Keough as Kate Jeffries

Gina Menza as Mrs. Jeffries

Per Didrik Fasmer as Mr. Jeffries

Michelle Joyner as Sherry Mauldin

Donald Forrest as Mack Mauldin

Julie Pierce as Erica Mauldin

Tim Ransom as Tommy Hull

Michelle M. Miller as Darla Hull

Maury Sterling as Sandman One

Michael Emanuel as Sandman One Co-Pilot

Lucas Dudley as Viper One Pilot

Robert Alan Joseph as Viper Two Pilot

Joseph Latimore as Viper Two Co-Pilot

Michael Sottile as Gunner Pilot

Ed Beechner as Gunner

Matthew Saks as Sergeant Wolf

Diana Bellamy as Mrs. Pananides

Lance Kerwin as American Mercenary

Brett Oliver as Belgian Mercenary

Eric Mungai Nguku as African Nurse

Larry Hine as Young McClintock

Nickolas H. Marshall as Young Ford

Douglas Hebron as Ju-Ju Man

Jae Woo Lee as Korean Captain

Johnny Kim as Seaman Chulso Lee

Bill Stevenson as Biotest Guard

Kellie Overbey as Alice

Dana Andersen as Corinne

Patricia Place as Mrs. Foote

Nicholas Pappone as Little Boy on Plane

Traci Odom as Little Boy's Mother

Herbert Jefferson Jr. as Boston Doctor #1

Thomas Crawford as Boston Doctor #2

Buzz Barbee as Boston Doctor #3

Jenna Byrne as Tracy

Brian Reddy as Tracy's Father

Ina Romeo as Mrs. Logan

Teresa Velarde as Nurse Emma

Jane Jenkins as Nurse Jane

Carmela Rappazzo as Hospital Receptionist

Kurt A. Boesen as Mayor Gaddis

Jack Rader as Police Chief Fowler

Robert Rigamonti as Country Health Official

Mimi Doyka as Frightened Mother

C. Jack Robinson as Biotest Manager

Robert Alan Beuth as George Armistead

Gordon Michaels as Man in Line

Peter Looney as White House Counsel

Conrad Bachmann as California Governor

Cary J. Pitts as Anchorman

Cynthia Harrison as Co-Anchor

Marcus Hennessy as Station Manager

Albert Owens as Broadcast Director

David Silverbrand as TV Reporter

Julie Araskog as Janet Adams

Frank Rositani as Senator Rosales

George Christy as Senator

Bruce Isacson as Jaffe

Marilyn Brandt as Ford's Secretary

Philip Handy as Sergeant Meyer

Tim Frazee as MP #1

Moses Williams as MP #2

Roland Tsui as MP #3

Keith Butler as MP #4

Davi Lee Phillips as MP #5

Ralph Miller as Officer #1

Mark Brown as Officer #2

Jim Antonio as Dr. Drew Reynolds

Ellsworth Hanna as Sailor at Cocktail Party (uncredited)

Jeanne Hanna as Sailor's Wife at Cocktail Party (uncredited)

Bruce Holman as Aide to White House Chief-of-Staff (uncredited)

Jack Kyle as Doctor (uncredited)

Bob Lazar as General (uncredited)

John Lizzi as Newsroom Reporter (uncredited)

Beau Lotterman as Army Major (uncredited)

David Novak as Diplomat (uncredited)

Ross Turner as Townsperson (uncredited)

J. T. Walsh as Chief of Staff (uncredited)

David A.R. White as Army Pilot (uncredited)

Robert 'Bobby Z' Zajonc as Army Pilot (uncredited)

Binx as Monkey